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Nano-drug delivery system for pancreatic cancer: A visualization and bibliometric analysis

Background: Nano drug delivery system (NDDS) can significantly improve the delivery and efficacy of drugs against pancreatic cancer (PC) in many ways. The purpose of this study is to explore the related research fields of NDDS for PC from the perspective of bibliometrics. Methods: Articles and revie...

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Autores principales: Zhao, Jie-Feng, Zou, Fei-Long, Zhu, Jin-Feng, Huang, Chao, Bu, Fan-Qin, Zhu, Zheng-Ming, Yuan, Rong-Fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622975/
https://www.ncbi.nlm.nih.gov/pubmed/36330100
http://dx.doi.org/10.3389/fphar.2022.1025618
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author Zhao, Jie-Feng
Zou, Fei-Long
Zhu, Jin-Feng
Huang, Chao
Bu, Fan-Qin
Zhu, Zheng-Ming
Yuan, Rong-Fa
author_facet Zhao, Jie-Feng
Zou, Fei-Long
Zhu, Jin-Feng
Huang, Chao
Bu, Fan-Qin
Zhu, Zheng-Ming
Yuan, Rong-Fa
author_sort Zhao, Jie-Feng
collection PubMed
description Background: Nano drug delivery system (NDDS) can significantly improve the delivery and efficacy of drugs against pancreatic cancer (PC) in many ways. The purpose of this study is to explore the related research fields of NDDS for PC from the perspective of bibliometrics. Methods: Articles and reviews on NDDS for PC published between 2003 and 2022 were obtained from the Web of Science Core Collection. CiteSpace, VOSviewer, R-bibliometrix, and Microsoft Excel were comprehensively used for bibliometric and visual analysis. Results: A total of 1329 papers on NDDS for PC were included. The number of papers showed an upward trend over the past 20 years. The United States contributed the most papers, followed by China, and India. Also, the United States had the highest number of total citations and H-index. The institution with the most papers was Chinese Acad Sci, which was also the most important in international institutional cooperation. Professors Couvreur P and Kazuoka K made great achievements in this field. JOURNAL OF CONTROLLED RELEASE published the most papers and was cited the most. The topics related to the tumor microenvironment such as “tumor microenvironment”, “tumor penetration”, “hypoxia”, “exosome”, and “autophagy”, PC treatment-related topics such as “immunotherapy”, “combination therapy”, “alternating magnetic field/magnetic hyperthermia”, and “ultrasound”, and gene therapy dominated by “siRNA” and “miRNA” were the research hotspots in the field of NDDS for PC. Conclusion: This study systematically uncovered a holistic picture of the performance of NDDS for PC-related literature over the past 20 years. We provided scholars to understand key information in this field with the perspective of bibliometrics, which we believe may greatly facilitate future research in this field.
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spelling pubmed-96229752022-11-02 Nano-drug delivery system for pancreatic cancer: A visualization and bibliometric analysis Zhao, Jie-Feng Zou, Fei-Long Zhu, Jin-Feng Huang, Chao Bu, Fan-Qin Zhu, Zheng-Ming Yuan, Rong-Fa Front Pharmacol Pharmacology Background: Nano drug delivery system (NDDS) can significantly improve the delivery and efficacy of drugs against pancreatic cancer (PC) in many ways. The purpose of this study is to explore the related research fields of NDDS for PC from the perspective of bibliometrics. Methods: Articles and reviews on NDDS for PC published between 2003 and 2022 were obtained from the Web of Science Core Collection. CiteSpace, VOSviewer, R-bibliometrix, and Microsoft Excel were comprehensively used for bibliometric and visual analysis. Results: A total of 1329 papers on NDDS for PC were included. The number of papers showed an upward trend over the past 20 years. The United States contributed the most papers, followed by China, and India. Also, the United States had the highest number of total citations and H-index. The institution with the most papers was Chinese Acad Sci, which was also the most important in international institutional cooperation. Professors Couvreur P and Kazuoka K made great achievements in this field. JOURNAL OF CONTROLLED RELEASE published the most papers and was cited the most. The topics related to the tumor microenvironment such as “tumor microenvironment”, “tumor penetration”, “hypoxia”, “exosome”, and “autophagy”, PC treatment-related topics such as “immunotherapy”, “combination therapy”, “alternating magnetic field/magnetic hyperthermia”, and “ultrasound”, and gene therapy dominated by “siRNA” and “miRNA” were the research hotspots in the field of NDDS for PC. Conclusion: This study systematically uncovered a holistic picture of the performance of NDDS for PC-related literature over the past 20 years. We provided scholars to understand key information in this field with the perspective of bibliometrics, which we believe may greatly facilitate future research in this field. Frontiers Media S.A. 2022-10-18 /pmc/articles/PMC9622975/ /pubmed/36330100 http://dx.doi.org/10.3389/fphar.2022.1025618 Text en Copyright © 2022 Zhao, Zou, Zhu, Huang, Bu, Zhu and Yuan. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Zhao, Jie-Feng
Zou, Fei-Long
Zhu, Jin-Feng
Huang, Chao
Bu, Fan-Qin
Zhu, Zheng-Ming
Yuan, Rong-Fa
Nano-drug delivery system for pancreatic cancer: A visualization and bibliometric analysis
title Nano-drug delivery system for pancreatic cancer: A visualization and bibliometric analysis
title_full Nano-drug delivery system for pancreatic cancer: A visualization and bibliometric analysis
title_fullStr Nano-drug delivery system for pancreatic cancer: A visualization and bibliometric analysis
title_full_unstemmed Nano-drug delivery system for pancreatic cancer: A visualization and bibliometric analysis
title_short Nano-drug delivery system for pancreatic cancer: A visualization and bibliometric analysis
title_sort nano-drug delivery system for pancreatic cancer: a visualization and bibliometric analysis
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622975/
https://www.ncbi.nlm.nih.gov/pubmed/36330100
http://dx.doi.org/10.3389/fphar.2022.1025618
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