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Personalized nutrition, microbiota, and metabolism: A triad for eudaimonia
During the previous few years, the relationship between the gut microbiota, metabolic disorders, and diet has come to light, especially due to the understanding of the mechanisms that particularly link the gut microbiota with obesity in animal models and clinical trials. Research has led to the unde...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623024/ https://www.ncbi.nlm.nih.gov/pubmed/36330221 http://dx.doi.org/10.3389/fmolb.2022.1038830 |
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author | Sarfraz, Muhammad Hassan Shahid, Aqsa Asghar, Samra Aslam, Bilal Ashfaq, Usman Ali Raza, Hammad Prieto, Miguel A. Simal-Gandara, Jesus Barba, Francisco J. Rajoka, Muhammad Shahid Riaz Khurshid, Mohsin Nashwan, Abdulqadir J. |
author_facet | Sarfraz, Muhammad Hassan Shahid, Aqsa Asghar, Samra Aslam, Bilal Ashfaq, Usman Ali Raza, Hammad Prieto, Miguel A. Simal-Gandara, Jesus Barba, Francisco J. Rajoka, Muhammad Shahid Riaz Khurshid, Mohsin Nashwan, Abdulqadir J. |
author_sort | Sarfraz, Muhammad Hassan |
collection | PubMed |
description | During the previous few years, the relationship between the gut microbiota, metabolic disorders, and diet has come to light, especially due to the understanding of the mechanisms that particularly link the gut microbiota with obesity in animal models and clinical trials. Research has led to the understanding that the responses of individuals to dietary inputs vary remarkably therefore no single diet can be suggested to every individual. The variations are attributed to differences in the microbiome and host characteristics. In general, it is believed that the immanent nature of host-derived factors makes them difficult to modulate. However, diet can more easily shape the microbiome, potentially influencing human physiology through modulation of digestion, absorption, mucosal immune response, and the availability of bioactive compounds. Thus, diet could be useful to influence the physiology of the host, as well as to ameliorate various disorders. In the present study, we have described recent developments in understanding the disparities of gut microbiota populations between individuals and the primary role of diet-microbiota interactions in modulating human physiology. A deeper understanding of these relationships can be useful for proposing personalized nutrition strategies and nutrition-based therapeutic interventions to improve human health. |
format | Online Article Text |
id | pubmed-9623024 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-96230242022-11-02 Personalized nutrition, microbiota, and metabolism: A triad for eudaimonia Sarfraz, Muhammad Hassan Shahid, Aqsa Asghar, Samra Aslam, Bilal Ashfaq, Usman Ali Raza, Hammad Prieto, Miguel A. Simal-Gandara, Jesus Barba, Francisco J. Rajoka, Muhammad Shahid Riaz Khurshid, Mohsin Nashwan, Abdulqadir J. Front Mol Biosci Molecular Biosciences During the previous few years, the relationship between the gut microbiota, metabolic disorders, and diet has come to light, especially due to the understanding of the mechanisms that particularly link the gut microbiota with obesity in animal models and clinical trials. Research has led to the understanding that the responses of individuals to dietary inputs vary remarkably therefore no single diet can be suggested to every individual. The variations are attributed to differences in the microbiome and host characteristics. In general, it is believed that the immanent nature of host-derived factors makes them difficult to modulate. However, diet can more easily shape the microbiome, potentially influencing human physiology through modulation of digestion, absorption, mucosal immune response, and the availability of bioactive compounds. Thus, diet could be useful to influence the physiology of the host, as well as to ameliorate various disorders. In the present study, we have described recent developments in understanding the disparities of gut microbiota populations between individuals and the primary role of diet-microbiota interactions in modulating human physiology. A deeper understanding of these relationships can be useful for proposing personalized nutrition strategies and nutrition-based therapeutic interventions to improve human health. Frontiers Media S.A. 2022-10-18 /pmc/articles/PMC9623024/ /pubmed/36330221 http://dx.doi.org/10.3389/fmolb.2022.1038830 Text en Copyright © 2022 Sarfraz, Shahid, Asghar, Aslam, Ashfaq, Raza, Prieto, Simal-Gandara, Barba, Rajoka, Khurshid and Nashwan. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Molecular Biosciences Sarfraz, Muhammad Hassan Shahid, Aqsa Asghar, Samra Aslam, Bilal Ashfaq, Usman Ali Raza, Hammad Prieto, Miguel A. Simal-Gandara, Jesus Barba, Francisco J. Rajoka, Muhammad Shahid Riaz Khurshid, Mohsin Nashwan, Abdulqadir J. Personalized nutrition, microbiota, and metabolism: A triad for eudaimonia |
title | Personalized nutrition, microbiota, and metabolism: A triad for eudaimonia |
title_full | Personalized nutrition, microbiota, and metabolism: A triad for eudaimonia |
title_fullStr | Personalized nutrition, microbiota, and metabolism: A triad for eudaimonia |
title_full_unstemmed | Personalized nutrition, microbiota, and metabolism: A triad for eudaimonia |
title_short | Personalized nutrition, microbiota, and metabolism: A triad for eudaimonia |
title_sort | personalized nutrition, microbiota, and metabolism: a triad for eudaimonia |
topic | Molecular Biosciences |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623024/ https://www.ncbi.nlm.nih.gov/pubmed/36330221 http://dx.doi.org/10.3389/fmolb.2022.1038830 |
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