Cargando…
Bosniak classification of cystic renal masses, version 2019: Is it helpful to incorporate the diffusion weighted imaging characteristic of lesions into the guideline?
OBJECTIVE: To improve understanding of diffusion weighted imaging (DWI) characteristic of MRI and clinical variables, further optimize the Bosniak classification for diagnosis of cystic renal masses (CRMs). METHODS: This study retrospectively analyzed 130 CRMs in 125 patients with CT or MRI, includi...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623058/ https://www.ncbi.nlm.nih.gov/pubmed/36330478 http://dx.doi.org/10.3389/fonc.2022.1004690 |
_version_ | 1784821909773352960 |
---|---|
author | Li, Anqin Li, Shichao Hu, Yao Shen, Yaqi Hu, Xuemei Hu, Daoyu Kamel, Ihab R. Li, Zhen |
author_facet | Li, Anqin Li, Shichao Hu, Yao Shen, Yaqi Hu, Xuemei Hu, Daoyu Kamel, Ihab R. Li, Zhen |
author_sort | Li, Anqin |
collection | PubMed |
description | OBJECTIVE: To improve understanding of diffusion weighted imaging (DWI) characteristic of MRI and clinical variables, further optimize the Bosniak classification for diagnosis of cystic renal masses (CRMs). METHODS: This study retrospectively analyzed 130 CRMs in 125 patients with CT or MRI, including 87 patients with DWI (b = 600, 1000 s/mm2). Clinical variables and histopathological results were recorded. Two radiologists in consensus analyzed images of each lesion for the size, thickness of wall, number of septum, enhancement of wall/septum, wall nodule, signal intensity on DWI, calcification, and cyst content. Clinical variables, CT and MRI image characteristics were compared with pathology or follow-up results to evaluate the diagnostic performance for CRMs. RESULTS: Of the 130 lesions in 125 patients, histological analysis reported that 36 were malignant, 38 were benign, and no change was found in 56 followed-up lesions (mean follow-up of 24 months). The incidences of cystic wall thickened, more septa, measurable enhancement of wall/septum, nodule(s) on CT/MRI, and high signal intensity on DWI were significantly higher in malignant than in benign CRMs (CT: p = 0.005, p < 0.001, p < 0.001, p < 0.001, p < 0.001; MRI: p < 0.001, p < 0.001, p < 0.001, p < 0.001, p < 0.001, p < 0.001). Combination of MRI including DWI features with CT findings showed the highest area under ROC curve (0.973) in distinguishing benign and malignant CRMs. CONCLUSIONS: Incorporating DWI characteristic of CRMs into Bosniak classification helps to improve diagnostic efficiency. |
format | Online Article Text |
id | pubmed-9623058 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-96230582022-11-02 Bosniak classification of cystic renal masses, version 2019: Is it helpful to incorporate the diffusion weighted imaging characteristic of lesions into the guideline? Li, Anqin Li, Shichao Hu, Yao Shen, Yaqi Hu, Xuemei Hu, Daoyu Kamel, Ihab R. Li, Zhen Front Oncol Oncology OBJECTIVE: To improve understanding of diffusion weighted imaging (DWI) characteristic of MRI and clinical variables, further optimize the Bosniak classification for diagnosis of cystic renal masses (CRMs). METHODS: This study retrospectively analyzed 130 CRMs in 125 patients with CT or MRI, including 87 patients with DWI (b = 600, 1000 s/mm2). Clinical variables and histopathological results were recorded. Two radiologists in consensus analyzed images of each lesion for the size, thickness of wall, number of septum, enhancement of wall/septum, wall nodule, signal intensity on DWI, calcification, and cyst content. Clinical variables, CT and MRI image characteristics were compared with pathology or follow-up results to evaluate the diagnostic performance for CRMs. RESULTS: Of the 130 lesions in 125 patients, histological analysis reported that 36 were malignant, 38 were benign, and no change was found in 56 followed-up lesions (mean follow-up of 24 months). The incidences of cystic wall thickened, more septa, measurable enhancement of wall/septum, nodule(s) on CT/MRI, and high signal intensity on DWI were significantly higher in malignant than in benign CRMs (CT: p = 0.005, p < 0.001, p < 0.001, p < 0.001, p < 0.001; MRI: p < 0.001, p < 0.001, p < 0.001, p < 0.001, p < 0.001, p < 0.001). Combination of MRI including DWI features with CT findings showed the highest area under ROC curve (0.973) in distinguishing benign and malignant CRMs. CONCLUSIONS: Incorporating DWI characteristic of CRMs into Bosniak classification helps to improve diagnostic efficiency. Frontiers Media S.A. 2022-10-18 /pmc/articles/PMC9623058/ /pubmed/36330478 http://dx.doi.org/10.3389/fonc.2022.1004690 Text en Copyright © 2022 Li, Li, Hu, Shen, Hu, Hu, Kamel and Li https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Li, Anqin Li, Shichao Hu, Yao Shen, Yaqi Hu, Xuemei Hu, Daoyu Kamel, Ihab R. Li, Zhen Bosniak classification of cystic renal masses, version 2019: Is it helpful to incorporate the diffusion weighted imaging characteristic of lesions into the guideline? |
title | Bosniak classification of cystic renal masses, version 2019: Is it helpful to incorporate the diffusion weighted imaging characteristic of lesions into the guideline? |
title_full | Bosniak classification of cystic renal masses, version 2019: Is it helpful to incorporate the diffusion weighted imaging characteristic of lesions into the guideline? |
title_fullStr | Bosniak classification of cystic renal masses, version 2019: Is it helpful to incorporate the diffusion weighted imaging characteristic of lesions into the guideline? |
title_full_unstemmed | Bosniak classification of cystic renal masses, version 2019: Is it helpful to incorporate the diffusion weighted imaging characteristic of lesions into the guideline? |
title_short | Bosniak classification of cystic renal masses, version 2019: Is it helpful to incorporate the diffusion weighted imaging characteristic of lesions into the guideline? |
title_sort | bosniak classification of cystic renal masses, version 2019: is it helpful to incorporate the diffusion weighted imaging characteristic of lesions into the guideline? |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623058/ https://www.ncbi.nlm.nih.gov/pubmed/36330478 http://dx.doi.org/10.3389/fonc.2022.1004690 |
work_keys_str_mv | AT lianqin bosniakclassificationofcysticrenalmassesversion2019isithelpfultoincorporatethediffusionweightedimagingcharacteristicoflesionsintotheguideline AT lishichao bosniakclassificationofcysticrenalmassesversion2019isithelpfultoincorporatethediffusionweightedimagingcharacteristicoflesionsintotheguideline AT huyao bosniakclassificationofcysticrenalmassesversion2019isithelpfultoincorporatethediffusionweightedimagingcharacteristicoflesionsintotheguideline AT shenyaqi bosniakclassificationofcysticrenalmassesversion2019isithelpfultoincorporatethediffusionweightedimagingcharacteristicoflesionsintotheguideline AT huxuemei bosniakclassificationofcysticrenalmassesversion2019isithelpfultoincorporatethediffusionweightedimagingcharacteristicoflesionsintotheguideline AT hudaoyu bosniakclassificationofcysticrenalmassesversion2019isithelpfultoincorporatethediffusionweightedimagingcharacteristicoflesionsintotheguideline AT kamelihabr bosniakclassificationofcysticrenalmassesversion2019isithelpfultoincorporatethediffusionweightedimagingcharacteristicoflesionsintotheguideline AT lizhen bosniakclassificationofcysticrenalmassesversion2019isithelpfultoincorporatethediffusionweightedimagingcharacteristicoflesionsintotheguideline |