Cargando…

Bosniak classification of cystic renal masses, version 2019: Is it helpful to incorporate the diffusion weighted imaging characteristic of lesions into the guideline?

OBJECTIVE: To improve understanding of diffusion weighted imaging (DWI) characteristic of MRI and clinical variables, further optimize the Bosniak classification for diagnosis of cystic renal masses (CRMs). METHODS: This study retrospectively analyzed 130 CRMs in 125 patients with CT or MRI, includi...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Anqin, Li, Shichao, Hu, Yao, Shen, Yaqi, Hu, Xuemei, Hu, Daoyu, Kamel, Ihab R., Li, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623058/
https://www.ncbi.nlm.nih.gov/pubmed/36330478
http://dx.doi.org/10.3389/fonc.2022.1004690
_version_ 1784821909773352960
author Li, Anqin
Li, Shichao
Hu, Yao
Shen, Yaqi
Hu, Xuemei
Hu, Daoyu
Kamel, Ihab R.
Li, Zhen
author_facet Li, Anqin
Li, Shichao
Hu, Yao
Shen, Yaqi
Hu, Xuemei
Hu, Daoyu
Kamel, Ihab R.
Li, Zhen
author_sort Li, Anqin
collection PubMed
description OBJECTIVE: To improve understanding of diffusion weighted imaging (DWI) characteristic of MRI and clinical variables, further optimize the Bosniak classification for diagnosis of cystic renal masses (CRMs). METHODS: This study retrospectively analyzed 130 CRMs in 125 patients with CT or MRI, including 87 patients with DWI (b = 600, 1000 s/mm2). Clinical variables and histopathological results were recorded. Two radiologists in consensus analyzed images of each lesion for the size, thickness of wall, number of septum, enhancement of wall/septum, wall nodule, signal intensity on DWI, calcification, and cyst content. Clinical variables, CT and MRI image characteristics were compared with pathology or follow-up results to evaluate the diagnostic performance for CRMs. RESULTS: Of the 130 lesions in 125 patients, histological analysis reported that 36 were malignant, 38 were benign, and no change was found in 56 followed-up lesions (mean follow-up of 24 months). The incidences of cystic wall thickened, more septa, measurable enhancement of wall/septum, nodule(s) on CT/MRI, and high signal intensity on DWI were significantly higher in malignant than in benign CRMs (CT: p = 0.005, p < 0.001, p < 0.001, p < 0.001, p < 0.001; MRI: p < 0.001, p < 0.001, p < 0.001, p < 0.001, p < 0.001, p < 0.001). Combination of MRI including DWI features with CT findings showed the highest area under ROC curve (0.973) in distinguishing benign and malignant CRMs. CONCLUSIONS: Incorporating DWI characteristic of CRMs into Bosniak classification helps to improve diagnostic efficiency.
format Online
Article
Text
id pubmed-9623058
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-96230582022-11-02 Bosniak classification of cystic renal masses, version 2019: Is it helpful to incorporate the diffusion weighted imaging characteristic of lesions into the guideline? Li, Anqin Li, Shichao Hu, Yao Shen, Yaqi Hu, Xuemei Hu, Daoyu Kamel, Ihab R. Li, Zhen Front Oncol Oncology OBJECTIVE: To improve understanding of diffusion weighted imaging (DWI) characteristic of MRI and clinical variables, further optimize the Bosniak classification for diagnosis of cystic renal masses (CRMs). METHODS: This study retrospectively analyzed 130 CRMs in 125 patients with CT or MRI, including 87 patients with DWI (b = 600, 1000 s/mm2). Clinical variables and histopathological results were recorded. Two radiologists in consensus analyzed images of each lesion for the size, thickness of wall, number of septum, enhancement of wall/septum, wall nodule, signal intensity on DWI, calcification, and cyst content. Clinical variables, CT and MRI image characteristics were compared with pathology or follow-up results to evaluate the diagnostic performance for CRMs. RESULTS: Of the 130 lesions in 125 patients, histological analysis reported that 36 were malignant, 38 were benign, and no change was found in 56 followed-up lesions (mean follow-up of 24 months). The incidences of cystic wall thickened, more septa, measurable enhancement of wall/septum, nodule(s) on CT/MRI, and high signal intensity on DWI were significantly higher in malignant than in benign CRMs (CT: p = 0.005, p < 0.001, p < 0.001, p < 0.001, p < 0.001; MRI: p < 0.001, p < 0.001, p < 0.001, p < 0.001, p < 0.001, p < 0.001). Combination of MRI including DWI features with CT findings showed the highest area under ROC curve (0.973) in distinguishing benign and malignant CRMs. CONCLUSIONS: Incorporating DWI characteristic of CRMs into Bosniak classification helps to improve diagnostic efficiency. Frontiers Media S.A. 2022-10-18 /pmc/articles/PMC9623058/ /pubmed/36330478 http://dx.doi.org/10.3389/fonc.2022.1004690 Text en Copyright © 2022 Li, Li, Hu, Shen, Hu, Hu, Kamel and Li https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Li, Anqin
Li, Shichao
Hu, Yao
Shen, Yaqi
Hu, Xuemei
Hu, Daoyu
Kamel, Ihab R.
Li, Zhen
Bosniak classification of cystic renal masses, version 2019: Is it helpful to incorporate the diffusion weighted imaging characteristic of lesions into the guideline?
title Bosniak classification of cystic renal masses, version 2019: Is it helpful to incorporate the diffusion weighted imaging characteristic of lesions into the guideline?
title_full Bosniak classification of cystic renal masses, version 2019: Is it helpful to incorporate the diffusion weighted imaging characteristic of lesions into the guideline?
title_fullStr Bosniak classification of cystic renal masses, version 2019: Is it helpful to incorporate the diffusion weighted imaging characteristic of lesions into the guideline?
title_full_unstemmed Bosniak classification of cystic renal masses, version 2019: Is it helpful to incorporate the diffusion weighted imaging characteristic of lesions into the guideline?
title_short Bosniak classification of cystic renal masses, version 2019: Is it helpful to incorporate the diffusion weighted imaging characteristic of lesions into the guideline?
title_sort bosniak classification of cystic renal masses, version 2019: is it helpful to incorporate the diffusion weighted imaging characteristic of lesions into the guideline?
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623058/
https://www.ncbi.nlm.nih.gov/pubmed/36330478
http://dx.doi.org/10.3389/fonc.2022.1004690
work_keys_str_mv AT lianqin bosniakclassificationofcysticrenalmassesversion2019isithelpfultoincorporatethediffusionweightedimagingcharacteristicoflesionsintotheguideline
AT lishichao bosniakclassificationofcysticrenalmassesversion2019isithelpfultoincorporatethediffusionweightedimagingcharacteristicoflesionsintotheguideline
AT huyao bosniakclassificationofcysticrenalmassesversion2019isithelpfultoincorporatethediffusionweightedimagingcharacteristicoflesionsintotheguideline
AT shenyaqi bosniakclassificationofcysticrenalmassesversion2019isithelpfultoincorporatethediffusionweightedimagingcharacteristicoflesionsintotheguideline
AT huxuemei bosniakclassificationofcysticrenalmassesversion2019isithelpfultoincorporatethediffusionweightedimagingcharacteristicoflesionsintotheguideline
AT hudaoyu bosniakclassificationofcysticrenalmassesversion2019isithelpfultoincorporatethediffusionweightedimagingcharacteristicoflesionsintotheguideline
AT kamelihabr bosniakclassificationofcysticrenalmassesversion2019isithelpfultoincorporatethediffusionweightedimagingcharacteristicoflesionsintotheguideline
AT lizhen bosniakclassificationofcysticrenalmassesversion2019isithelpfultoincorporatethediffusionweightedimagingcharacteristicoflesionsintotheguideline