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Rare-earth doped BiFe(0.95)Mn(0.05)O(3) nanoparticles for potential hyperthermia applications

Ionic engineering is exploited to substitute Bi cations in BiFe(0.95)Mn(0.05)O(3) NPs (BFM) with rare-earth (RE) elements (Nd, Gd, and Dy). The sol-gel synthesized RE-NPs are tested for their magnetic hyperthermia potential. RE-dopants alter the morphology of BFM NPs from elliptical to rectangular t...

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Autores principales: Dubey, Astita, Salamon, Soma, Attanayake, Supun B., Ibrahim, Syaidah, Landers, Joachim, Castillo, Marianela Escobar, Wende, Heiko, Srikanth, Hari, Shvartsman, Vladimir V., Lupascu, Doru C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623096/
https://www.ncbi.nlm.nih.gov/pubmed/36329706
http://dx.doi.org/10.3389/fbioe.2022.965146
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author Dubey, Astita
Salamon, Soma
Attanayake, Supun B.
Ibrahim, Syaidah
Landers, Joachim
Castillo, Marianela Escobar
Wende, Heiko
Srikanth, Hari
Shvartsman, Vladimir V.
Lupascu, Doru C.
author_facet Dubey, Astita
Salamon, Soma
Attanayake, Supun B.
Ibrahim, Syaidah
Landers, Joachim
Castillo, Marianela Escobar
Wende, Heiko
Srikanth, Hari
Shvartsman, Vladimir V.
Lupascu, Doru C.
author_sort Dubey, Astita
collection PubMed
description Ionic engineering is exploited to substitute Bi cations in BiFe(0.95)Mn(0.05)O(3) NPs (BFM) with rare-earth (RE) elements (Nd, Gd, and Dy). The sol-gel synthesized RE-NPs are tested for their magnetic hyperthermia potential. RE-dopants alter the morphology of BFM NPs from elliptical to rectangular to irregular hexagonal for Nd, Gd, and Dy doping, respectively. The RE-BFM NPs are ferroelectric and show larger piezoresponse than the pristine BFO NPs. There is an increase of the maximum magnetization at 300 K of BFM up to 550% by introducing Gd. In hyperthermia tests, 3 mg/ml dispersion of NPs in water and agar could increase the temperature of the dispersion up to ∼39°C under an applied AC magnetic field of 80 mT. Although Gd doping generates the highest increment in magnetization of BFM NPs, the Dy-BFM NPs show the best hyperthermia results. These findings show that RE-doped BFO NPs are promising for hyperthermia and other biomedical applications.
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spelling pubmed-96230962022-11-02 Rare-earth doped BiFe(0.95)Mn(0.05)O(3) nanoparticles for potential hyperthermia applications Dubey, Astita Salamon, Soma Attanayake, Supun B. Ibrahim, Syaidah Landers, Joachim Castillo, Marianela Escobar Wende, Heiko Srikanth, Hari Shvartsman, Vladimir V. Lupascu, Doru C. Front Bioeng Biotechnol Bioengineering and Biotechnology Ionic engineering is exploited to substitute Bi cations in BiFe(0.95)Mn(0.05)O(3) NPs (BFM) with rare-earth (RE) elements (Nd, Gd, and Dy). The sol-gel synthesized RE-NPs are tested for their magnetic hyperthermia potential. RE-dopants alter the morphology of BFM NPs from elliptical to rectangular to irregular hexagonal for Nd, Gd, and Dy doping, respectively. The RE-BFM NPs are ferroelectric and show larger piezoresponse than the pristine BFO NPs. There is an increase of the maximum magnetization at 300 K of BFM up to 550% by introducing Gd. In hyperthermia tests, 3 mg/ml dispersion of NPs in water and agar could increase the temperature of the dispersion up to ∼39°C under an applied AC magnetic field of 80 mT. Although Gd doping generates the highest increment in magnetization of BFM NPs, the Dy-BFM NPs show the best hyperthermia results. These findings show that RE-doped BFO NPs are promising for hyperthermia and other biomedical applications. Frontiers Media S.A. 2022-10-18 /pmc/articles/PMC9623096/ /pubmed/36329706 http://dx.doi.org/10.3389/fbioe.2022.965146 Text en Copyright © 2022 Dubey, Salamon, Attanayake, Ibrahim, Landers, Castillo, Wende, Srikanth, Shvartsman and Lupascu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Dubey, Astita
Salamon, Soma
Attanayake, Supun B.
Ibrahim, Syaidah
Landers, Joachim
Castillo, Marianela Escobar
Wende, Heiko
Srikanth, Hari
Shvartsman, Vladimir V.
Lupascu, Doru C.
Rare-earth doped BiFe(0.95)Mn(0.05)O(3) nanoparticles for potential hyperthermia applications
title Rare-earth doped BiFe(0.95)Mn(0.05)O(3) nanoparticles for potential hyperthermia applications
title_full Rare-earth doped BiFe(0.95)Mn(0.05)O(3) nanoparticles for potential hyperthermia applications
title_fullStr Rare-earth doped BiFe(0.95)Mn(0.05)O(3) nanoparticles for potential hyperthermia applications
title_full_unstemmed Rare-earth doped BiFe(0.95)Mn(0.05)O(3) nanoparticles for potential hyperthermia applications
title_short Rare-earth doped BiFe(0.95)Mn(0.05)O(3) nanoparticles for potential hyperthermia applications
title_sort rare-earth doped bife(0.95)mn(0.05)o(3) nanoparticles for potential hyperthermia applications
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623096/
https://www.ncbi.nlm.nih.gov/pubmed/36329706
http://dx.doi.org/10.3389/fbioe.2022.965146
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