Tollip negatively regulates mitophagy by promoting the mitochondrial processing and cytoplasmic release of PINK1

PTEN-induced putative kinase 1 (PINK1) is a serine/threonine kinase that phosphorylates several substrates and exerts neuroprotective effects against stress-induced apoptotic cell death. Mutations in PINK1 have been linked to autosomal recessive forms of Parkinson’s disease (PD). Mitophagy is a type...

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Detalles Bibliográficos
Autores principales: Shin, Woo Hyun, Chung, Kwang Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623242/
https://www.ncbi.nlm.nih.gov/pubmed/35725015
http://dx.doi.org/10.5483/BMBRep.2022.55.10.082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623242/
https://www.ncbi.nlm.nih.gov/pubmed/35725015
http://dx.doi.org/10.5483/BMBRep.2022.55.10.082

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