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Temporal Profile of Kynurenine Pathway Metabolites in a Rodent Model of Autosomal Recessive Polycystic Kidney Disease

Autosomal recessive polycystic kidney disease (ARPKD) is an early onset genetic disorder characterized by numerous renal cysts resulting in end stage renal disease. Our study aimed to determine if metabolic reprogramming and tryptophan (Trp) metabolism via the kynurenine pathway (KP) is a critical d...

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Detalles Bibliográficos
Autores principales:	Pires, Ananda Staats, Gupta, Shabarni, Barton, Sean A, Vander Wall, Roshana, Tan, Vanessa, Heng, Benjamin, Phillips, Jacqueline K, Guillemin, Gilles J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623391/ https://www.ncbi.nlm.nih.gov/pubmed/36329761 http://dx.doi.org/10.1177/11786469221126063

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