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A systems biological analysis of the ATF4‐GADD34‐CHOP regulatory triangle upon endoplasmic reticulum stress

Endoplasmic reticulum (ER) stress‐dependent accumulation of incorrectly folded proteins leads to activation of the unfolded protein response. The role of the unfolded protein response (UPR) is to avoid cell damage and restore the homeostatic state by autophagy; however, excessive ER stress results i...

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Detalles Bibliográficos
Autores principales: Márton, Margita, Bánhegyi, Gábor, Gyöngyösi, Norbert, Kálmán, Eszter Éva, Pettkó‐Szandtner, Aladár, Káldi, Krisztina, Kapuy, Orsolya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623533/
https://www.ncbi.nlm.nih.gov/pubmed/36097827
http://dx.doi.org/10.1002/2211-5463.13484