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Acacetin improves cognitive function of APP/PS1 Alzheimer’s disease model mice via the NLRP3 inflammasome signaling pathway
BACKGROUND: Acacetin (5,7-dihydroxy-4′-methoxyflavone), one of the main extractions from Saussurea involucrata, has anti-inflammatory effects. Our previous study found that acacetin inhibited the Nod-like receptor pyrin domain containing 3 (NLRP3) signaling pathway after cerebral ischemia–reperfusio...
Autores principales: | Bu, Juan, Zhang, Yanmin, Mahan, Yeledan, Shi, Shen, Wu, Xuanxia, Zhang, Xiaoling, Wang, Zhaoxia, Zhou, Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623727/ https://www.ncbi.nlm.nih.gov/pubmed/36382256 http://dx.doi.org/10.1515/tnsci-2022-0254 |
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