A rare case of sarcoidosis with necrotizing mediastinal lymphadenitis misdiagnosed as multidrug-resistant tuberculosis (MDR- TB)

Sarcoidosis, a multisystem disorder of unknown cause, is characterized by the presence of non-caseating granulomas and the proliferation of epithelioid cells. Sarcoidosis mostly affects the lungs and mediastinal lymph nodes in 90% of cases. Caseation and necrosis are very rare. We report the present...

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Autores principales: Prasad, Rajendra, Shamim, Huda, Kacker, Rishabh, Gupta, Nikhil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623855/
https://www.ncbi.nlm.nih.gov/pubmed/36629210
http://dx.doi.org/10.4103/lungindia.lungindia_16_22
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author Prasad, Rajendra
Shamim, Huda
Kacker, Rishabh
Gupta, Nikhil
author_facet Prasad, Rajendra
Shamim, Huda
Kacker, Rishabh
Gupta, Nikhil
author_sort Prasad, Rajendra
collection PubMed
description Sarcoidosis, a multisystem disorder of unknown cause, is characterized by the presence of non-caseating granulomas and the proliferation of epithelioid cells. Sarcoidosis mostly affects the lungs and mediastinal lymph nodes in 90% of cases. Caseation and necrosis are very rare. We report the present case in view of its rarity, as sarcoidosis with significant necrosis in mediastinal lymph nodes is a rare phenomenon and can mislead the treating physician into diagnosing it as tuberculosis, which can lead to exposure of the patient to undue side effects of anti-tubercular drugs.
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spelling pubmed-96238552022-11-02 A rare case of sarcoidosis with necrotizing mediastinal lymphadenitis misdiagnosed as multidrug-resistant tuberculosis (MDR- TB) Prasad, Rajendra Shamim, Huda Kacker, Rishabh Gupta, Nikhil Lung India Case Report Sarcoidosis, a multisystem disorder of unknown cause, is characterized by the presence of non-caseating granulomas and the proliferation of epithelioid cells. Sarcoidosis mostly affects the lungs and mediastinal lymph nodes in 90% of cases. Caseation and necrosis are very rare. We report the present case in view of its rarity, as sarcoidosis with significant necrosis in mediastinal lymph nodes is a rare phenomenon and can mislead the treating physician into diagnosing it as tuberculosis, which can lead to exposure of the patient to undue side effects of anti-tubercular drugs. Wolters Kluwer - Medknow 2022 2022-08-29 /pmc/articles/PMC9623855/ /pubmed/36629210 http://dx.doi.org/10.4103/lungindia.lungindia_16_22 Text en Copyright: © 2022 Indian Chest Society https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Prasad, Rajendra
Shamim, Huda
Kacker, Rishabh
Gupta, Nikhil
A rare case of sarcoidosis with necrotizing mediastinal lymphadenitis misdiagnosed as multidrug-resistant tuberculosis (MDR- TB)
title A rare case of sarcoidosis with necrotizing mediastinal lymphadenitis misdiagnosed as multidrug-resistant tuberculosis (MDR- TB)
title_full A rare case of sarcoidosis with necrotizing mediastinal lymphadenitis misdiagnosed as multidrug-resistant tuberculosis (MDR- TB)
title_fullStr A rare case of sarcoidosis with necrotizing mediastinal lymphadenitis misdiagnosed as multidrug-resistant tuberculosis (MDR- TB)
title_full_unstemmed A rare case of sarcoidosis with necrotizing mediastinal lymphadenitis misdiagnosed as multidrug-resistant tuberculosis (MDR- TB)
title_short A rare case of sarcoidosis with necrotizing mediastinal lymphadenitis misdiagnosed as multidrug-resistant tuberculosis (MDR- TB)
title_sort rare case of sarcoidosis with necrotizing mediastinal lymphadenitis misdiagnosed as multidrug-resistant tuberculosis (mdr- tb)
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623855/
https://www.ncbi.nlm.nih.gov/pubmed/36629210
http://dx.doi.org/10.4103/lungindia.lungindia_16_22
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