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Genome-wide DNA methylation analysis of extreme phenotypes in the identification of novel epigenetic modifications in diabetic retinopathy

BACKGROUND: Aberrant epigenetic modifications such as DNA methylation may contribute to the pathogenesis of DR. We aimed at elucidating the role of novel DNA methylation modifications in diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (T2DM) using an extreme phenotypic design. ME...

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Detalles Bibliográficos
Autores principales:	Yang, Shaopeng, Guo, Xiao, Cheng, Weijing, Seth, Ishith, Bulloch, Gabriella, Chen, Yifan, Shang, Xianwen, Zhu, Zhuoting, Huang, Wenyong, Wang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623976/ https://www.ncbi.nlm.nih.gov/pubmed/36316758 http://dx.doi.org/10.1186/s13148-022-01354-z

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