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Excessive IL-15 promotes cytotoxic CD4 + CD28− T cell-mediated renal injury in lupus nephritis

BACKGROUND: Patients with systemic lupus erythematosus (SLE) are highly susceptible to infection and cardiovascular events, suggesting that chronic antigenic stimulation may accelerate premature aging in SLE patients. Premature aging in SLE is often accompanied with the expansion of cytotoxic CD4 + ...

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Detalles Bibliográficos
Autores principales:	Zhang, Ti, Liu, Xin, Zhao, Yue, Xu, Xiaodong, Liu, Yaoyang, Wu, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624042/ https://www.ncbi.nlm.nih.gov/pubmed/36320075 http://dx.doi.org/10.1186/s12979-022-00305-9

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