In-house testing for homologous recombination repair deficiency (HRD) testing in ovarian carcinoma: a feasibility study comparing AmoyDx HRD Focus panel with Myriad myChoiceCDx assay

BACKGROUND: Homologous recombination repair (HRR) is the main mechanism of repair of DNA double-strand breaks. Its deficiency (HRD) is a common feature of epithelial ovarian cancers (EOCs). BRCA1/2 mutations and/or other aberrations in genes of HRR are well known causes of HRD and genomic instabilit...

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Detalles Bibliográficos
Autores principales: Fumagalli, Caterina, Betella, Ilaria, Ranghiero, Alberto, Guerini-Rocco, Elena, Bonaldo, Giulio, Rappa, Alessandra, Vacirca, Davide, Colombo, Nicoletta, Barberis, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pacini Editore srl 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624133/
https://www.ncbi.nlm.nih.gov/pubmed/36136896
http://dx.doi.org/10.32074/1591-951X-791

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