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Highly Sensitive Detection of Isoniazid Heteroresistance in Mycobacterium Tuberculosis by Droplet Digital PCR

PURPOSE: The drug resistance of Mycobacterium tuberculosis constitutes a major public health threat. Existing approaches make it challenging to detect low levels of drug-resistant TB, also known as heteroresistance (HR), in a population. The recently found droplet digital PCR (ddPCR) is a sensitive...

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Detalles Bibliográficos
Autores principales: Zheng, Yang, Xia, Hui, Bao, Xundi, Zhao, Bing, He, Ping, Zhao, Yanlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624153/
https://www.ncbi.nlm.nih.gov/pubmed/36329987
http://dx.doi.org/10.2147/IDR.S381097