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Adhesion of Asian Dust Particles to Verofilcon a Soft Contact Lenses

PURPOSE: Asian dust poses a serious global health hazard. Airborne particles adhering to contact lenses may cause substantial damage to the ocular surface. The recently released one-day disposable silicone hydrogel soft contact lens (SCL), the verofilcon A, has a smooth surface with SMARTSURFACE(®)...

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Autores principales: Mimura, Tatsuya, Fujishima, Hiroshi, Uchio, Eichi, Fukagawa, Kazumi, Inoue, Yuji, Kawashima, Makoto, Kitsu, Kazuma, Mizota, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624171/
https://www.ncbi.nlm.nih.gov/pubmed/36329953
http://dx.doi.org/10.2147/OPTO.S381763
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author Mimura, Tatsuya
Fujishima, Hiroshi
Uchio, Eichi
Fukagawa, Kazumi
Inoue, Yuji
Kawashima, Makoto
Kitsu, Kazuma
Mizota, Atsushi
author_facet Mimura, Tatsuya
Fujishima, Hiroshi
Uchio, Eichi
Fukagawa, Kazumi
Inoue, Yuji
Kawashima, Makoto
Kitsu, Kazuma
Mizota, Atsushi
author_sort Mimura, Tatsuya
collection PubMed
description PURPOSE: Asian dust poses a serious global health hazard. Airborne particles adhering to contact lenses may cause substantial damage to the ocular surface. The recently released one-day disposable silicone hydrogel soft contact lens (SCL), the verofilcon A, has a smooth surface with SMARTSURFACE(®) technology, which is designed to prevent adhesion of protein components and foreign bodies. The purpose of this study was to verify the protective quality of verofilcon A SCL against adhesion of Asian dust particles to its surface. METHODS: Verofilcon A and etafilcon A (control lens) SCLs were used (n=16 per group), and 0.2 mL of physiological saline containing 0.01 mg/mL of Asian dust particles was dropped on the surface of SCLs, allowed to stand for 1 hour, shaken for 1 minute, and rinsed three times with saline (after rinsing). In addition, the samples were agitated by a vortex mixer for 1 minute and rinsed three times with saline (after vortex). The number of Asian dust particles adhering to the SCLs and percentage of the surface area occupied by the Asian dust particles was determined before washing, after rinsing, and after vortexing. RESULTS: The number of adherent Asian dust particles was lower on verofilcon A SCL (297 ± 116 after rinsing, and 5 ± 14 after vortexing) than on etafilcon A SCL (523 ± 212 after rinsing, p=0.003, and 378 ± 268 after vortexing, p<0.001). The Asian dust adhesion area was also lower on verofilcon A SCL (3.6 ± 2.3% after rinsing and 0.0 ± 0.1% after vortexing than on etafilcon A (10.2 ± 2.1% after rinsing, p=0.002, and 5.2 ± 3.0% after vortexing, p<0.001). CONCLUSION: These findings indicate that verofilcon A SCL has the property of low adhesion of Asian dust particles. Verofilcon A SCL can be recommended for SCL wearers during windy and Asian dust days.
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spelling pubmed-96241712022-11-02 Adhesion of Asian Dust Particles to Verofilcon a Soft Contact Lenses Mimura, Tatsuya Fujishima, Hiroshi Uchio, Eichi Fukagawa, Kazumi Inoue, Yuji Kawashima, Makoto Kitsu, Kazuma Mizota, Atsushi Clin Optom (Auckl) Original Research PURPOSE: Asian dust poses a serious global health hazard. Airborne particles adhering to contact lenses may cause substantial damage to the ocular surface. The recently released one-day disposable silicone hydrogel soft contact lens (SCL), the verofilcon A, has a smooth surface with SMARTSURFACE(®) technology, which is designed to prevent adhesion of protein components and foreign bodies. The purpose of this study was to verify the protective quality of verofilcon A SCL against adhesion of Asian dust particles to its surface. METHODS: Verofilcon A and etafilcon A (control lens) SCLs were used (n=16 per group), and 0.2 mL of physiological saline containing 0.01 mg/mL of Asian dust particles was dropped on the surface of SCLs, allowed to stand for 1 hour, shaken for 1 minute, and rinsed three times with saline (after rinsing). In addition, the samples were agitated by a vortex mixer for 1 minute and rinsed three times with saline (after vortex). The number of Asian dust particles adhering to the SCLs and percentage of the surface area occupied by the Asian dust particles was determined before washing, after rinsing, and after vortexing. RESULTS: The number of adherent Asian dust particles was lower on verofilcon A SCL (297 ± 116 after rinsing, and 5 ± 14 after vortexing) than on etafilcon A SCL (523 ± 212 after rinsing, p=0.003, and 378 ± 268 after vortexing, p<0.001). The Asian dust adhesion area was also lower on verofilcon A SCL (3.6 ± 2.3% after rinsing and 0.0 ± 0.1% after vortexing than on etafilcon A (10.2 ± 2.1% after rinsing, p=0.002, and 5.2 ± 3.0% after vortexing, p<0.001). CONCLUSION: These findings indicate that verofilcon A SCL has the property of low adhesion of Asian dust particles. Verofilcon A SCL can be recommended for SCL wearers during windy and Asian dust days. Dove 2022-10-28 /pmc/articles/PMC9624171/ /pubmed/36329953 http://dx.doi.org/10.2147/OPTO.S381763 Text en © 2022 Mimura et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Mimura, Tatsuya
Fujishima, Hiroshi
Uchio, Eichi
Fukagawa, Kazumi
Inoue, Yuji
Kawashima, Makoto
Kitsu, Kazuma
Mizota, Atsushi
Adhesion of Asian Dust Particles to Verofilcon a Soft Contact Lenses
title Adhesion of Asian Dust Particles to Verofilcon a Soft Contact Lenses
title_full Adhesion of Asian Dust Particles to Verofilcon a Soft Contact Lenses
title_fullStr Adhesion of Asian Dust Particles to Verofilcon a Soft Contact Lenses
title_full_unstemmed Adhesion of Asian Dust Particles to Verofilcon a Soft Contact Lenses
title_short Adhesion of Asian Dust Particles to Verofilcon a Soft Contact Lenses
title_sort adhesion of asian dust particles to verofilcon a soft contact lenses
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624171/
https://www.ncbi.nlm.nih.gov/pubmed/36329953
http://dx.doi.org/10.2147/OPTO.S381763
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