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Deep mendelian randomization: Investigating the causal knowledge of genomic deep learning models

Multi-task deep learning (DL) models can accurately predict diverse genomic marks from sequence, but whether these models learn the causal relationships between genomic marks is unknown. Here, we describe Deep Mendelian Randomization (DeepMR), a method for estimating causal relationships between gen...

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Detalles Bibliográficos
Autores principales: Malina, Stephen, Cizin, Daniel, Knowles, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624391/
https://www.ncbi.nlm.nih.gov/pubmed/36265006
http://dx.doi.org/10.1371/journal.pcbi.1009880