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Pyoderma Gangrenosum Affecting the Dorsal Hand: A Case Report

Pyoderma gangrenosum is an uncommon neutrophilic dermatosis characterized by an ulcerative lesion with a violaceous border. Most frequently, these lesions present in the lower extremity and are associated with underlying immune-mediated comorbidities. Infrequently, these lesions may present in the u...

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Autores principales: Haase, Lucas R., Nelson, Grant B., Klyce, Walter B., Cavaliere, Christi M., Bafus, Blaine T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624498/
https://www.ncbi.nlm.nih.gov/pubmed/36337430
http://dx.doi.org/10.1097/GOX.0000000000004592
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author Haase, Lucas R.
Nelson, Grant B.
Klyce, Walter B.
Cavaliere, Christi M.
Bafus, Blaine T.
author_facet Haase, Lucas R.
Nelson, Grant B.
Klyce, Walter B.
Cavaliere, Christi M.
Bafus, Blaine T.
author_sort Haase, Lucas R.
collection PubMed
description Pyoderma gangrenosum is an uncommon neutrophilic dermatosis characterized by an ulcerative lesion with a violaceous border. Most frequently, these lesions present in the lower extremity and are associated with underlying immune-mediated comorbidities. Infrequently, these lesions may present in the upper extremity, which presents difficult challenges for upper extremity surgeons as the lesions are frequently misdiagnosed as an infectious process. This often leads to inappropriate surgical debridement and antibiotic administration. Local trauma to the lesion can lead to a process of pathergy and worsening of the lesion. Here, we report on a case of cutaneous pyoderma gangrenosum affecting the dorsal hand, originally misidentified as an atypical infection with subsequent unsuccessful surgical debridement. After involvement of a multidisciplinary team, appropriate diagnosis was made, and treatment with local immunosuppressive agents achieved resolution of the lesion.
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spelling pubmed-96244982022-11-03 Pyoderma Gangrenosum Affecting the Dorsal Hand: A Case Report Haase, Lucas R. Nelson, Grant B. Klyce, Walter B. Cavaliere, Christi M. Bafus, Blaine T. Plast Reconstr Surg Glob Open Hand Pyoderma gangrenosum is an uncommon neutrophilic dermatosis characterized by an ulcerative lesion with a violaceous border. Most frequently, these lesions present in the lower extremity and are associated with underlying immune-mediated comorbidities. Infrequently, these lesions may present in the upper extremity, which presents difficult challenges for upper extremity surgeons as the lesions are frequently misdiagnosed as an infectious process. This often leads to inappropriate surgical debridement and antibiotic administration. Local trauma to the lesion can lead to a process of pathergy and worsening of the lesion. Here, we report on a case of cutaneous pyoderma gangrenosum affecting the dorsal hand, originally misidentified as an atypical infection with subsequent unsuccessful surgical debridement. After involvement of a multidisciplinary team, appropriate diagnosis was made, and treatment with local immunosuppressive agents achieved resolution of the lesion. Lippincott Williams & Wilkins 2022-11-01 /pmc/articles/PMC9624498/ /pubmed/36337430 http://dx.doi.org/10.1097/GOX.0000000000004592 Text en Copyright © 2022 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Hand
Haase, Lucas R.
Nelson, Grant B.
Klyce, Walter B.
Cavaliere, Christi M.
Bafus, Blaine T.
Pyoderma Gangrenosum Affecting the Dorsal Hand: A Case Report
title Pyoderma Gangrenosum Affecting the Dorsal Hand: A Case Report
title_full Pyoderma Gangrenosum Affecting the Dorsal Hand: A Case Report
title_fullStr Pyoderma Gangrenosum Affecting the Dorsal Hand: A Case Report
title_full_unstemmed Pyoderma Gangrenosum Affecting the Dorsal Hand: A Case Report
title_short Pyoderma Gangrenosum Affecting the Dorsal Hand: A Case Report
title_sort pyoderma gangrenosum affecting the dorsal hand: a case report
topic Hand
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624498/
https://www.ncbi.nlm.nih.gov/pubmed/36337430
http://dx.doi.org/10.1097/GOX.0000000000004592
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