RF06 | PSAT154 Osteoporosis Likely Increases the Risk of Dementia in Vietnamese Immigrants

Osteoporosis is a common systemic skeletal disease that predominantly affects people older than 50 years and often co-occurs with dementia. Studies have been conducted to find out the relation between the two, but this is not well studied in the Vietnamese population. This study aimed to analyze the impact of osteoporosis on the risk of dementia in Vietnamese immigrants. We identified 38(female(F) 26, male(M) 12) community-dwelling Vietnamese patients aged ≥ 55 seen at the cognitive assessment clinic in a community health center 1/2021-8/2021 through chart review. Because either DEXA was not performed or the results were unavailable, 23 patients (F 12, M 11) were excluded. We assigned the patients with normal cognitive tests results or a diagnosis of mild cognitive impairment to the control group and those diagnosed with dementia to the study group. Among 15 patients, 10(F 9, M 1) patients were diagnosed with dementia. Seven patients (F 6, M 1) had osteoporosis. Five patients (F 5) were assigned to the control group, and two patients had osteoporosis. (OR 3.5000, P = 0.2736) The odds of developing dementia were 3.5 higher given osteoporosis diagnosis than with no osteoporosis. These results suggested a positive association between osteoporosis and dementia in Vietnamese immigrants. More studies with a larger number of patients in this cohort are needed to investigate this further. Presentation: Saturday, June 11, 2022 1:00 p.m. - 3:00 p.m., Saturday, June 11, 2022 1:18 p.m. - 1:23 p.m.