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PSUN136 CCN5/WISP2 gene deficiency improves insulin sensitivity and glucose tolerance in diet-induced obesity, especially in male mice
: CCN5/WISP2 is a matricellular protein, the expression of which is under the regulation of Wnt signaling and IGF-1. Our initial characterization supports the notion that CCN5 promotes the proliferation and survival of pancreatic β-cells leading to metabolic benefits [1]. Recently, the effects of C...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624652/ http://dx.doi.org/10.1210/jendso/bvac150.749 |