ODP011 Single Nuclei RNA-Sequencing of Frozen Human Adipose Tissue and PET/CT Imaging Coupled With Deep-Learning Reveals Single-Cell Landscape and Transcriptional Dynamics Related to Adipocyte Hypertrophy and in Vivo Dysmetabolism

BACKGROUND: Adipocyte hypertrophy is associated with glucose and lipid dysmetabolism, ectopic fat accumulation, and metabolic complications independently of the level of obesity [1]. In this study, we aimed to explore potential mechanisms driving the obesity-independent, hypertrophy-associated dysme...

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Detalles Bibliográficos
Autores principales: Ye, Run Zhou, Montastier, Emilie, Frisch, Frédérique, Noll, Christophe, Allard-Chamard, Hugues, Gévry, Nicolas, Tchernof, André, Carpentier, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Adipose Tissue, Appetite, & Obesity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624784/
http://dx.doi.org/10.1210/jendso/bvac150.025

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