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OR24-3 GPR31 Mediates the Proinflammatory Reponses in the Setting of Diabetic Inflammation

The pathogenesis of type 1 diabetes (T1D) involves the interaction of the immune system with pancreatic islets, featured by inflammation in both macrophages and β cells. The enzyme 12-lipoxygenase (12-LOX) is expressed in macrophages and β-cells, produces the eicosanoid 12(S)-HETE and promotes infla...

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Detalles Bibliográficos
Autores principales:	Anderson, Ryan, Avadhanam, Sriya, Kulkarni, Abhishek, Mirmira, Raghavendra, Nelson, Jennifer, Tersey, Sarah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Diabetes & Glucose Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624811/ http://dx.doi.org/10.1210/jendso/bvac150.731

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