LBODP008 Gene Therapy For Congenital Adrenal Hyperplasia With AAV Vectors Into Fibroblasts, IPS Cells And Model Mice

BACKGROUND: Congenital adrenal hyperplasia (CAH) is due to defects of steroid synthetic enzymes, which includes microsomal and mitochondrial P450s. Microsomal P450s include 21-hydroxylase and 17α-hydroxylase/17-lyase. 21-hydroxylase deficiency (21-OHD), in which CYP21A2 is mutated or deleted, is the...

Descripción completa

Detalles Bibliográficos
Autores principales: Naiki, Yasuhiro, Miyado, Mami, Horikawa, Reiko, Katsumata, Noriyuki, Takada, Shuji, Akutsu, Hidenori, Onodera, Masafumi, Fukami, Maki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Adrenal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624819/
http://dx.doi.org/10.1210/jendso/bvac150.084

Ejemplares similares

Ejemplares similares