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ODP607 Long-term Efficacy of Setmelanotide in Patients With POMC or LEPR Deficiency Obesity

The melanocortin-4 receptor (MC4R) pathway in the brain is responsible for energy regulation, affecting appetite and body weight. Impairments of this pathway can result in hyperphagia (insatiable hunger) and obesity. The MC4R can be impacted by the POMC, PCSK1, or LEPR genes. Variants in these genes...

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Detalles Bibliográficos
Autores principales:	Clément, Karine, Wabitsch, Martin, Van den Akker, Erica, Argente, Jesús, Scimia, Ceclila, Srinivasan, Madhura, Yuan, Guojun, Kühnen, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Adipose Tissue, Appetite, & Obesity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624830/ http://dx.doi.org/10.1210/jendso/bvac150.030

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