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RF12 | PSUN106 Quantifying Liver and Brain Levels of 11β-hydroxysteroid Dehydrogenase Type 1 in Obesity Using Positron Emission Tomography Imaging

OBJECTIVES: Cortisol is known to promote adipocyte differentiation and maturation, and prolonged exposure to excess cortisol contributes to the development of obesity and metabolic dysregulation. The intracellular 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme catalyzes the conversion of...

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Detalles Bibliográficos
Autores principales:	Bini, Jason, Gallezot, Jean-Dominique, Li, Songye, Lim, Keunpoong, Emery, Paul, Kapinos, Michael, Ropchan, Jim, Nabulsi, Nabeel, Jastreboff, Ania, Huang, Yiyun, Carson, Richard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Adipose Tissue, Appetite, & Obesity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624872/ http://dx.doi.org/10.1210/jendso/bvac150.062

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