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RF12 | PSUN106 Quantifying Liver and Brain Levels of 11β-hydroxysteroid Dehydrogenase Type 1 in Obesity Using Positron Emission Tomography Imaging
OBJECTIVES: Cortisol is known to promote adipocyte differentiation and maturation, and prolonged exposure to excess cortisol contributes to the development of obesity and metabolic dysregulation. The intracellular 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme catalyzes the conversion of...
Autores principales: | Bini, Jason, Gallezot, Jean-Dominique, Li, Songye, Lim, Keunpoong, Emery, Paul, Kapinos, Michael, Ropchan, Jim, Nabulsi, Nabeel, Jastreboff, Ania, Huang, Yiyun, Carson, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624872/ http://dx.doi.org/10.1210/jendso/bvac150.062 |
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