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PSAT073 The Human Gonads Do Not Contribute to the Circulating Pool of 11-Oxygenated Androgens

BACKGROUND: Androstenedione (A4) and testosterone (T) are produced by both the adrenal glands and the gonads. The adrenal enzyme steroid 11β-hydroxylase (CYP11B1) executes the last step in cortisol synthesis; CYP11B1 also uses A4 and T as substrates, generating 11-hydroxyadrostenedione (11OHA4) and...

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Detalles Bibliográficos
Autores principales: Rabbah, Amira, Davio, Angela, Liu, Haiping, Marko, Xhorlina, Sherk, William, Rege, Juilee, Rainey, William, Turcu, Adina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624911/
http://dx.doi.org/10.1210/jendso/bvac150.231