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LBODP040 Positive Early Glucola Screening: Who Has Gestational Diabetes?
This study set out to determine risk factors most predictive of early GDMA review was conducted of patients with positive early 1HR glucola screenings (≥135 mg/dL and reflex 3hr GTT before 20 weeks). Characteristics (comorbidities, family history, demographics) of patients who were diagnosed with ea...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624955/ http://dx.doi.org/10.1210/jendso/bvac150.550 |
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author | Class, Madelyn Sharma, Ankita Durgham, Ryan Anasti, James N |
author_facet | Class, Madelyn Sharma, Ankita Durgham, Ryan Anasti, James N |
author_sort | Class, Madelyn |
collection | PubMed |
description | This study set out to determine risk factors most predictive of early GDMA review was conducted of patients with positive early 1HR glucola screenings (≥135 mg/dL and reflex 3hr GTT before 20 weeks). Characteristics (comorbidities, family history, demographics) of patients who were diagnosed with early GDM were compared to those who were not. A multiple logistic regression model was constructed to compute adjusted odds ratios (aORs) for each covariate. Among 189 early GDM positive (BMI 36.1 ± 8.27; Age 32.7 ± 5.50) and 153 GDM negative (BMI 33.8 ± 7.24; Age 30.8 ± 5.45) patients were identified, the adjusted odds of developing GDM increases by: 6.7% (CI 1. 01-1.12; p 0. 01) or 4.5% (CI 1. 01-1. 08; p 0. 02) with a one unit increase in age or BMI, respectively. The aORs of developing GDM are 2. 0 (CI 1.24-3.26, p 0. 005), 3. 0 (CI 1.64-5.66; p 0. 0005), and 3.7 (CI 1.96-8.78, p 0. 0003) with family history of diabetes, prior history of GDM, or history of hypertension, respectively. This study was unique in that hypertension had the highest association with early GDM. Thus, individuals with HTN regardless of age, BMI, prior GDM, family history should receive an early glucola screen. Presentation: No date and time listed |
format | Online Article Text |
id | pubmed-9624955 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-96249552022-11-14 LBODP040 Positive Early Glucola Screening: Who Has Gestational Diabetes? Class, Madelyn Sharma, Ankita Durgham, Ryan Anasti, James N J Endocr Soc Diabetes & Glucose Metabolism This study set out to determine risk factors most predictive of early GDMA review was conducted of patients with positive early 1HR glucola screenings (≥135 mg/dL and reflex 3hr GTT before 20 weeks). Characteristics (comorbidities, family history, demographics) of patients who were diagnosed with early GDM were compared to those who were not. A multiple logistic regression model was constructed to compute adjusted odds ratios (aORs) for each covariate. Among 189 early GDM positive (BMI 36.1 ± 8.27; Age 32.7 ± 5.50) and 153 GDM negative (BMI 33.8 ± 7.24; Age 30.8 ± 5.45) patients were identified, the adjusted odds of developing GDM increases by: 6.7% (CI 1. 01-1.12; p 0. 01) or 4.5% (CI 1. 01-1. 08; p 0. 02) with a one unit increase in age or BMI, respectively. The aORs of developing GDM are 2. 0 (CI 1.24-3.26, p 0. 005), 3. 0 (CI 1.64-5.66; p 0. 0005), and 3.7 (CI 1.96-8.78, p 0. 0003) with family history of diabetes, prior history of GDM, or history of hypertension, respectively. This study was unique in that hypertension had the highest association with early GDM. Thus, individuals with HTN regardless of age, BMI, prior GDM, family history should receive an early glucola screen. Presentation: No date and time listed Oxford University Press 2022-11-01 /pmc/articles/PMC9624955/ http://dx.doi.org/10.1210/jendso/bvac150.550 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the Endocrine Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Diabetes & Glucose Metabolism Class, Madelyn Sharma, Ankita Durgham, Ryan Anasti, James N LBODP040 Positive Early Glucola Screening: Who Has Gestational Diabetes? |
title | LBODP040 Positive Early Glucola Screening: Who Has Gestational Diabetes? |
title_full | LBODP040 Positive Early Glucola Screening: Who Has Gestational Diabetes? |
title_fullStr | LBODP040 Positive Early Glucola Screening: Who Has Gestational Diabetes? |
title_full_unstemmed | LBODP040 Positive Early Glucola Screening: Who Has Gestational Diabetes? |
title_short | LBODP040 Positive Early Glucola Screening: Who Has Gestational Diabetes? |
title_sort | lbodp040 positive early glucola screening: who has gestational diabetes? |
topic | Diabetes & Glucose Metabolism |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624955/ http://dx.doi.org/10.1210/jendso/bvac150.550 |
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