Cargando…

LBODP109 Astrocytes Affect The Metabolism Of Proopiomelanocortin (pomc) Neurons Through The Release Of Exosomes That Are Modified In A Fatty Acid Specific Manner

Astrocytes influence neighboring neurons through the release of a variety of signals, including exosomes, micro-vesicles that contain a vast heterogeneity of molecules such as cytokines, growth factors, RNAs and micro-RNAs (mi-RNAs) that modify target cells. We hypothesized that hypothalamic astrocy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Collado-Pérez, Roberto, Jiménez-Hernaiz, Maria, García-Piqueras, Jorge, Guerra-Cantera, Santiago, Argente, Jesús, Fernández-Marcos, Pablo J, Frago, Laura M, Chowen, Julie A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Adipose Tissue, Appetite, & Obesity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625029/ http://dx.doi.org/10.1210/jendso/bvac150.006

Ejemplares similares

Fatty Acids Modify the MicroRNA Content of Exosomes Released by Hypothalamic Astrocytes and the Response of POMC Neurons to These Exosomes
por: Collado-Pérez, Roberto, et al.
Publicado: (2021)

SAT-593 Sex-Specific Modifications in MicroRNAs Contained in Exosomes of Astrocytes in Response to Palmitic Acid
por: Chowen, Julie Ann, et al.
Publicado: (2020)

ODP607 Long-term Efficacy of Setmelanotide in Patients With POMC or LEPR Deficiency Obesity
por: Clément, Karine, et al.
Publicado: (2022)

OR10-1 Body Mass Index and Weight Reductions in Patients With Obesity Due to Heterozygous Variants in POMC, PCSK1, and LEPR After 1 Year of Setmelanotide
por: Farooqi, Sadaf, et al.
Publicado: (2022)

SUN-LB016 The Long Term Effects of Resveratrol Supplementation during Pregnancy and Lactation on Adipose Tissue Morphology in the Adult Offspring
por: Ros-Pérez, Purificación, et al.
Publicado: (2019)

RF24 | PSUN96 Setmelanotide in Patients With Heterozygous POMC, LEPR, SRC1, or SH2B1 Obesity: Design of EMANATE – A Placebo-Controlled Phase 3 Trial
por: Wabitsch, Martin, et al.
Publicado: (2022)

LBODP005 Gper Modulates Multiple Functions In Adipose Tissue To Promote An Anti-obese Phenotype
por: Sharma, Geetanjali, et al.
Publicado: (2022)

THU128 Transcription Factor ETV5 In POMC Neurons Regulate Energy And Glucose Homeostasis
por: Gahlot, Surbhi, et al.
Publicado: (2023)

LBODP001 Causal Associations Between Body Fat Accumulation and Covid-19 Severity: A Mendelian Randomization Study
por: Yoshiji, Satoshi, et al.
Publicado: (2022)

SUN-109 PTEN Regulates Differentiation and Proliferation of Aging Preadipocytes
por: Kirstein, Anna, et al.
Publicado: (2019)

SAT-596 POMC Expression in GABAergic Neurons Suppresses NPY Overexpression and Restores Food Intake in Obese Mice
por: Trotta, Milagros, et al.
Publicado: (2020)

LBODP003 Effects Of 4-weeks’ Treatment With Intraperitoneal Colchicine On Metabolic And Inflammatory Outcomes In Mice Fed A High-fat Diet
por: Arner, Brooke E, et al.
Publicado: (2022)

LBODP004 The Impact Of Covid-19 On Obesity And Ultra-processed Food Intake In Adolescents And Young Adults: Interim Analysis From The PIE Study
por: Balhara, Maria
Publicado: (2022)

Timing of Onset of Adverse Events With Setmelanotide, an MC4R Agonist, in Patients With Severe Obesity Due to LEPR or POMC Deficiency
por: Clément, Karine, et al.
Publicado: (2021)

LBODP002 Phase II Open-label Pilot Trial Of Liraglutide In Adolescents With Obesity After Vertical Sleeve Gastrectomy: Interim Results From 8-weeks Of Treatment
por: Fatima, Syeda Z, et al.
Publicado: (2022)

MON-109 Identifying Limiting Factors to Weight Loss and Prevention of Comorbidities in a Patient Population with Obesity
por: Johns, Allison, et al.
Publicado: (2019)

SAT-109 tiRNA-5 Reflects the Severity of Mitochondrial Oxidative Stress in Nonalcoholic Fatty Liver Disease
por: Yang, Yashuang, et al.
Publicado: (2019)

RF24 | PSUN109 Very Low Calorie Ketogenic Diet combined with interval training for preserving muscle mass during weight loss in sarcopenic obesity: a pilot study
por: Camajani, Elisabetta, et al.
Publicado: (2022)

SAT-LB107 Insulin Sensing by Astrocytes Is Critical for Normal Thermogenesis and Body Temperature Regulation
por: Hill, Jennifer Wootton, et al.
Publicado: (2020)

RF24 | PSUN91 Body Mass Index and Weight Reduction in Patients With SH2B1 Genetic Variant Obesity After One Year of Setmelanotide
por: Argente, Jesús, et al.
Publicado: (2022)

ODP605 Body Mass Index and Weight Reductions in Patients With SRC1 Genetic Variant Obesity After 1 Year of Setmelanotide
por: Martos-Moreno, Gabriel Á, et al.
Publicado: (2022)

OR12-6 Deletion Of The Brain-Specific α And δ Isoforms Of SH2B1 Protects Against Diet-Induced Obesity In A Leptin-Independent Manner
por: Cote, Jessica, et al.
Publicado: (2019)

ODP606 Long-term Efficacy of Setmelanotide in Patients With Bardet-Biedl Syndrome
por: Argente, Jesús, et al.
Publicado: (2022)

A Phase 3 Trial in Participants With Obesity Due to Bardet-Biedl Syndrome or Alström Syndrome: Efficacy and Safety of the Melanocortin 4 Receptor Agonist Setmelanotide
por: Haws, Robert, et al.
Publicado: (2021)

SAT-590 Role of Adipocyte Hyperplasia and Hypertrophy in the Release and Charge of Exosomes in Human Fat Cells
por: Vecchiola, Andrea, et al.
Publicado: (2020)

SAT-LB020 Use of Ultrasound to Characterize Abdominal Adipose Tissue Distribution and Its Impact on Metabolic Syndrome
por: Cuatrecasas Cambra, Guillem, et al.
Publicado: (2019)

MON-099 Age-Related Differences in Appetite Regulation among Adults with Obesity: More Than Just Hunger and PYY and Ghrelin? Oh My!
por: Iwamoto, Sean, et al.
Publicado: (2019)

MON-101 The LD Lync Study: Natural History Study of Lipodystrophy Syndromes: Early Lessons from the Pilot Data
por: Jalal Eldin, Abdelwahab, et al.
Publicado: (2019)

MON-114 Effect of Selective Mineralocorticoid Receptor Antagonist on liver Fat and Metabolism in Patients with Type 2 Diabetes: A Randomized Controlled Trail
por: Kistorp, Caroline, et al.
Publicado: (2019)

MON-092 Role of Genetic Variants of NNMT rs694539 and rs1941404, FTO rs1421085 and Irx3 rs3751723 Polymorphisms on Resting Energy Expenditure and BMI
por: Bañales Luna, Maciel, et al.
Publicado: (2019)

MON-113 Taste Sensitivity is Related to Incretin Response to Oral Glucose Challenge, Dietary Habits and Body Composition: A Novel Link with Energy Metabolism
por: Dagdelen, Selcuk, et al.
Publicado: (2019)

MON-106 Prevalence of Abdominal Obesity According to Different Cutoff Points in the Peruvian Population Living at Different Altitudes
por: Pajuelo-Ramirez, Jaime, et al.
Publicado: (2019)

MON-115 Acute BAT Activation Improves Glucose Tolerance and Beta-Cell Secretion and Facilities Lipid over Glucose Utilization in Obese Metabolically Healthy Males
por: Bertozzi, Beatrice, et al.
Publicado: (2019)

MON-098 FSH and Body Composition in Older Adults
por: Woods, Gina, et al.
Publicado: (2019)

MON-104 Defining the Contribution of Weight to the Extent of Metabolic Disease in FPLD: Insights from a Retrospective "Matched" Case-Control Study
por: Koo, Eden, et al.
Publicado: (2019)

SAT-102 Self-efficacy As A Predictor Of Weight Loss In Veterans With Obesity Participating In Medical Weight Management.
por: Parziale, Andrew, et al.
Publicado: (2019)

SAT-LB017 Anthropometric Imaging and Biological Markers of Adiposity and Aldosterone among African Americans: The Jackson Heart Study
por: Lee, Grace, et al.
Publicado: (2019)

MON-096 Body Composition in Patients with Craniopharyngioma: Is DXA-Scanning Necessary for Evaluating the Metabolic Syndrome?
por: van Santen, Selveta, et al.
Publicado: (2019)

MON-118 Biochemical and Clinical Correlates of Subcutaneous Adipose mRNA Transcript Levels in Men with T2DM
por: Tun, Nyo Nyo, et al.
Publicado: (2019)

MON-110 A Natural Compound Isolated from Schisandra Chinensis Fruit Has a Beneficial Effect in a Fly Model of Obesity
por: Cheon, Chong Kun, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_j86clmavvrrn3sfmm7k02q7pa3