OR18-1 The Impact of Makorin Ring Finger Protein 3 (MKRN3) Overexpression in the Arcuate Nucleus of Postpubertal Female Mice on the HPG Axis

BACKGROUND AND OBJECTIVE: Makorin Ring Finger Protein 3 (MKRN3), an inhibitor of the KISS1 and TAC3 promoters in the hypothalamic arcuate nucleus (ARC), is an important player in age of menarche and etiology of central precocious puberty. However, its potential role in delayed puberty and/or hypogon...

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Detalles Bibliográficos
Autores principales: Carroll, Rona, Kaiser, Ursula, Kim, Han Kyeol, McKnight, Kali, Naule, Lydie, Pereira, Sidney, Sena-Esteves, Miguel, Roberts, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Pediatric Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625226/
http://dx.doi.org/10.1210/jendso/bvac150.1278

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