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ODP483 Histone deacetylase 3 plays an important role in cerebellar developmental defects induced by hypothyroidism
BACKGROUND: Properly organized transcriptional regulation is responsible for the organogenesis of central nervous system including the cerebellum. Perinatal hypothyroidism impairs cerebellar organogenesis and results in motor coordination defects. In the absence of ligand, thyroid hormone receptor b...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625245/ http://dx.doi.org/10.1210/jendso/bvac150.1583 |