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RF03 | PMON296 Insulin-induced AKR1C3 Metabolizes Classical and 11-oxygenated Androgens in a Model of PCOS Adipocytes

Polycystic ovary syndrome (PCOS) is the most prevalent endocrinopathy in women. These patients commonly develop hyperandrogenism and this androgen excess (AE) is believed to drive the syndrome. PCOS women also characteristically develop insulin resistance (IR), which correlates with AE in PCOS women...

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Detalles Bibliográficos
Autores principales:	Mesaros, Clementina, Paulukinas, Ryan, Penning, Trevor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Steroid Hormones and Receptors
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625287/ http://dx.doi.org/10.1210/jendso/bvac150.1509

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