PMON171 DRD2 Agonist Cabergoline Abolished the Escape Mechanism Induced by mTOR Inhibitor Everolimus in Pituitary Neuroendocrine Tumoral Cells

PI3K-AKT-mTOR inhibitors have been proposed as alternative therapeutic strategy for tumors resistant to conventional drugs. The mammalian target of rapamycin (mTOR) inhibitor everolimus has been shown to display antiproliferative effects on a wide spectrum of tumors. In vitro studies demonstrated th...

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Detalles Bibliográficos
Autores principales: Mangili, Federica, Esposito, Emanuela, Treppiedi, Donatella, Catalano, Rosa, Marra, Giusy, Muro, Genesio D, Locatelli, Marco, Lania, Andrea Gerardo, Arosio, Maura, Mantovani, Giovanna, Peverelli, Erika Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Neuroendocrinology and Pituitary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625316/
http://dx.doi.org/10.1210/jendso/bvac150.1141

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