OR17-4 Hormone Replacement Promotes Sexual Maturation and Fertility Restoration in Mice With Congenital Hypopituitarism Harboring Prop1 Mutation

INTRODUCTION: The Ames strain, a spontaneous mutant mouse of the Prop1 gene, is deficient in GH, TSH, PRL and gonadotropins. In recent years, it has been the focus of studies on aging and there is a growing interest in elucidating the role of hormone replacement (HR) in the hypothalamic-pituitary-go...

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Detalles Bibliográficos
Autores principales: José da Cruz, Robison, Kaory Tamashiro, Leticia, Matera Veras, Mariana, Moreira Silva, Juliana, R S Carvalho, Luciani, Silvestre de Souza Trigueiro, Nicholas, Yuji Yariwake, Victor, Azevedo, Bruna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Neuroendocrinology and Pituitary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625369/
http://dx.doi.org/10.1210/jendso/bvac150.1090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625369/
http://dx.doi.org/10.1210/jendso/bvac150.1090

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