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OR17-4 Hormone Replacement Promotes Sexual Maturation and Fertility Restoration in Mice With Congenital Hypopituitarism Harboring Prop1 Mutation
INTRODUCTION: The Ames strain, a spontaneous mutant mouse of the Prop1 gene, is deficient in GH, TSH, PRL and gonadotropins. In recent years, it has been the focus of studies on aging and there is a growing interest in elucidating the role of hormone replacement (HR) in the hypothalamic-pituitary-go...
Autores principales: | José da Cruz, Robison, Kaory Tamashiro, Leticia, Matera Veras, Mariana, Moreira Silva, Juliana, R S Carvalho, Luciani, Silvestre de Souza Trigueiro, Nicholas, Yuji Yariwake, Victor, Azevedo, Bruna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625369/ http://dx.doi.org/10.1210/jendso/bvac150.1090 |
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