ODP602 A Rare Case of Nonfunctional Metastatic Pancreatic Neuroendocrine Tumor Transformation into an Insulin-secreting Tumor: A Management Dilemma

Pancreatic neuroendocrine tumors (PNETs) although rare, have recently increased in incidence . Clinically they can be classified as functional or nonfunctional depending on presence or absence of active hormone symptomatology and this has a bearing on prognosis and management . Rarely nonfunctioning...

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Detalles Bibliográficos
Autores principales: Azmath, Misbath, Faisal, Sobia, Kantorovich, Vitaly, Guruli, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Neuroendocrinology and Pituitary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625423/
http://dx.doi.org/10.1210/jendso/bvac150.1081
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author Azmath, Misbath
Faisal, Sobia
Kantorovich, Vitaly
Guruli, Marie
author_facet Azmath, Misbath
Faisal, Sobia
Kantorovich, Vitaly
Guruli, Marie
author_sort Azmath, Misbath
collection PubMed
description Pancreatic neuroendocrine tumors (PNETs) although rare, have recently increased in incidence . Clinically they can be classified as functional or nonfunctional depending on presence or absence of active hormone symptomatology and this has a bearing on prognosis and management . Rarely nonfunctioning tumors can undergo biological transformation into a hormone-secreting tumor. We present a rare clinical scenario of a young male with widely metastatic nonfunctional PNET who later presented with profound hypoglycemia with concerns for transformation into an insulin secreting tumor. Presentation: No date and time listed
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spelling pubmed-96254232022-11-14 ODP602 A Rare Case of Nonfunctional Metastatic Pancreatic Neuroendocrine Tumor Transformation into an Insulin-secreting Tumor: A Management Dilemma Azmath, Misbath Faisal, Sobia Kantorovich, Vitaly Guruli, Marie J Endocr Soc Neuroendocrinology and Pituitary Pancreatic neuroendocrine tumors (PNETs) although rare, have recently increased in incidence . Clinically they can be classified as functional or nonfunctional depending on presence or absence of active hormone symptomatology and this has a bearing on prognosis and management . Rarely nonfunctioning tumors can undergo biological transformation into a hormone-secreting tumor. We present a rare clinical scenario of a young male with widely metastatic nonfunctional PNET who later presented with profound hypoglycemia with concerns for transformation into an insulin secreting tumor. Presentation: No date and time listed Oxford University Press 2022-11-01 /pmc/articles/PMC9625423/ http://dx.doi.org/10.1210/jendso/bvac150.1081 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the Endocrine Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Neuroendocrinology and Pituitary
Azmath, Misbath
Faisal, Sobia
Kantorovich, Vitaly
Guruli, Marie
ODP602 A Rare Case of Nonfunctional Metastatic Pancreatic Neuroendocrine Tumor Transformation into an Insulin-secreting Tumor: A Management Dilemma
title ODP602 A Rare Case of Nonfunctional Metastatic Pancreatic Neuroendocrine Tumor Transformation into an Insulin-secreting Tumor: A Management Dilemma
title_full ODP602 A Rare Case of Nonfunctional Metastatic Pancreatic Neuroendocrine Tumor Transformation into an Insulin-secreting Tumor: A Management Dilemma
title_fullStr ODP602 A Rare Case of Nonfunctional Metastatic Pancreatic Neuroendocrine Tumor Transformation into an Insulin-secreting Tumor: A Management Dilemma
title_full_unstemmed ODP602 A Rare Case of Nonfunctional Metastatic Pancreatic Neuroendocrine Tumor Transformation into an Insulin-secreting Tumor: A Management Dilemma
title_short ODP602 A Rare Case of Nonfunctional Metastatic Pancreatic Neuroendocrine Tumor Transformation into an Insulin-secreting Tumor: A Management Dilemma
title_sort odp602 a rare case of nonfunctional metastatic pancreatic neuroendocrine tumor transformation into an insulin-secreting tumor: a management dilemma
topic Neuroendocrinology and Pituitary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625423/
http://dx.doi.org/10.1210/jendso/bvac150.1081
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