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ODP653 DNA Methylation Markers Detected in Liquid Biopsy Specimens Differentiate Pituitary Neuroendocrine Tumors from Other Sellar and CNS Diseases

BACKGROUND: DNA methylation abnormalities are pervasive in pituitary neuroendocrine tumors (PitNETs). The feasibility to detect these molecular alterations in circulating cell-free DNA (cfDNA) has been reported for several central nervous system tumors but not across PitNETs. HYPOTHESIS: PitNET-spec...

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Detalles Bibliográficos
Autores principales: Castro, Ana Valeria, Herrgott, Grayson, Asmaro, Karam, Wells, Michael, Sabedot, Thais, Barnholtz-Sloan, Jill, Sloan, Andrew, Selman, Warren, Noushmehr, Houtan, Rock, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625445/
http://dx.doi.org/10.1210/jendso/bvac150.1086