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OR26-2 mTOR Interacts with the Mineralocorticoid Receptor to Regulate its Activation by Ligand
BACKGROUND: Phosphorylation of the mineralocorticoid receptor (MR) at serine 843 inhibits its activity. mTOR phosphorylation of ULK1 prevents this MR phosphorylation. PURPOSE: To study the relationship between mTOR and MR and its role in the modulation of aldosterone signaling. METHODS: Mouse cortic...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625453/ http://dx.doi.org/10.1210/jendso/bvac150.1495 |