OR26-3 USP19 Deubiquitinating Enzyme Functions as a Novel Co-Chaperone of Hsp90 to Regulate Glucocorticoid Receptor Levels

Ubiquitin specific protease 19 (USP19) is a deubiquitinating enzyme involved in metabolism. Its expression is upregulated in skeletal muscle in many conditions of muscle wasting. Genetic inactivation of USP19 (USP19KO) in mice protects from muscle atrophy and diet induced obesity and insulin resista...

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Detalles Bibliográficos
Autores principales: Bedard, Nathalie, Coyne, Erin, Huynh, Julie, Jacq, Xavier, Rozycka, Ewelina, Schorova, Lenka, Young, Jason, Wing, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Steroid Hormones and Receptors
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625529/
http://dx.doi.org/10.1210/jendso/bvac150.1496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625529/
http://dx.doi.org/10.1210/jendso/bvac150.1496

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