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OR26-3 USP19 Deubiquitinating Enzyme Functions as a Novel Co-Chaperone of Hsp90 to Regulate Glucocorticoid Receptor Levels
Ubiquitin specific protease 19 (USP19) is a deubiquitinating enzyme involved in metabolism. Its expression is upregulated in skeletal muscle in many conditions of muscle wasting. Genetic inactivation of USP19 (USP19KO) in mice protects from muscle atrophy and diet induced obesity and insulin resista...
Autores principales: | Bedard, Nathalie, Coyne, Erin, Huynh, Julie, Jacq, Xavier, Rozycka, Ewelina, Schorova, Lenka, Young, Jason, Wing, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625529/ http://dx.doi.org/10.1210/jendso/bvac150.1496 |
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