ODP316 Hyponatremia as a Prognostic Factor for Mortality in COVID-19 at The National Hospital "Dos de Mayo", Lima Peru.

INTRODUCTION: Hyponatremia is the most common electrolyte disorder in hospitalized patients. It's more common in patients who were hospitalized with a diagnosed of pneumonia, which worsen the prognosis of the general condition. The infection in patients with SARS-CoV-2, can present hyponatremia, which would affect in a negativity way the recovery of them with mild, moderate or severe respiratory symptoms. OBJECTIVE: Establish if hyponatremia is a prognostic factor of mortality in patients with covid-19 diagnosis.Material and methods: The sample consisted of 185 medical records of patients with a COVID-19 diagnosis, which has been seen between June 2020 and February 2021 an observational, cohort and retrospective study. We recorded epidemiological, demographic, clinical, biochemical and radiological variables of SARS-CoV-2 infection and hyponatremia at the time of diagnosis during hospitalization. Descriptive analysis was used for main variables, Chi square tests, OR calculation and confidence interval were used to assess the statistical association of the variables. Finally, a logistic regression analysis was performed to evaluate confusing variables. RESULTS: 160 patients have hyponatremia (34.9% mild, 26.7% moderate and 40% severe) and none of them had a previous diagnosis of SIHAD (Syndrome of inappropriate antidiuretic hormone secretion) consigned in their clinical histories. The increase of mortality was consigned (viewed) in patients with severe hyponatremia compared with moderate and mild hyponatremia diagnosed at hospital admission (20.8% mild hyponatremia, 21.6% moderate and 46.4% severe, p=0. 03) CONCLUSION: Severe hyponatremia at hospital admission was associated with elevated mortality in SARSCoV-2 patients. Presentation: No date and time listed