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LBODP079 A Case of Silent Invasive Corticotroph Adenoma
ACTH-secreting pituitary adenomas account for about two-thirds of cases of endogenous Cushing's syndrome and are considered the most common cause of endogenous hypercortisolemia. Silent corticotroph adenomas (SCAs) are pituitary tumors that stain positive for adrenocorticotropic hormone (ACTH)...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625622/ http://dx.doi.org/10.1210/jendso/bvac150.995 |
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author | Bendaram, Snigdha Reddy Kantorovich, Vitaly |
author_facet | Bendaram, Snigdha Reddy Kantorovich, Vitaly |
author_sort | Bendaram, Snigdha Reddy |
collection | PubMed |
description | ACTH-secreting pituitary adenomas account for about two-thirds of cases of endogenous Cushing's syndrome and are considered the most common cause of endogenous hypercortisolemia. Silent corticotroph adenomas (SCAs) are pituitary tumors that stain positive for adrenocorticotropic hormone (ACTH) but do not produce biochemical levels of excess ACTH or cortisol. These tumors account for approximately 20% of all corticotroph adenomas and 5.5% of nonfunctioning pituitary adenomas. New immunohistochemical (IHC) techniques continue to be the gold standard in diagnosis, while having prognostic implications. Presentation: No date and time listed |
format | Online Article Text |
id | pubmed-9625622 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-96256222022-11-14 LBODP079 A Case of Silent Invasive Corticotroph Adenoma Bendaram, Snigdha Reddy Kantorovich, Vitaly J Endocr Soc Neuroendocrinology and Pituitary ACTH-secreting pituitary adenomas account for about two-thirds of cases of endogenous Cushing's syndrome and are considered the most common cause of endogenous hypercortisolemia. Silent corticotroph adenomas (SCAs) are pituitary tumors that stain positive for adrenocorticotropic hormone (ACTH) but do not produce biochemical levels of excess ACTH or cortisol. These tumors account for approximately 20% of all corticotroph adenomas and 5.5% of nonfunctioning pituitary adenomas. New immunohistochemical (IHC) techniques continue to be the gold standard in diagnosis, while having prognostic implications. Presentation: No date and time listed Oxford University Press 2022-11-01 /pmc/articles/PMC9625622/ http://dx.doi.org/10.1210/jendso/bvac150.995 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the Endocrine Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Neuroendocrinology and Pituitary Bendaram, Snigdha Reddy Kantorovich, Vitaly LBODP079 A Case of Silent Invasive Corticotroph Adenoma |
title | LBODP079 A Case of Silent Invasive Corticotroph Adenoma |
title_full | LBODP079 A Case of Silent Invasive Corticotroph Adenoma |
title_fullStr | LBODP079 A Case of Silent Invasive Corticotroph Adenoma |
title_full_unstemmed | LBODP079 A Case of Silent Invasive Corticotroph Adenoma |
title_short | LBODP079 A Case of Silent Invasive Corticotroph Adenoma |
title_sort | lbodp079 a case of silent invasive corticotroph adenoma |
topic | Neuroendocrinology and Pituitary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625622/ http://dx.doi.org/10.1210/jendso/bvac150.995 |
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