COVID-19 vaccination is associated with reduced non-COVID in-hospital mortality

We retrieved data on a cohort of medical patients at a regional Israeli hospital. The dependent variable was non-COVID-19 hospital mortality; the independent variables were vaccination status, age, and laboratory data. Serum sodium, age, serum creatinine, and COVID-19 vaccination status were the mai...

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Detalles Bibliográficos
Autores principales: Benbassat, Jochanan, Froom, Paul, Shimoni, Zvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625845/
https://www.ncbi.nlm.nih.gov/pubmed/36332771
http://dx.doi.org/10.1016/j.ypmed.2022.107326
Descripción
Sumario:We retrieved data on a cohort of medical patients at a regional Israeli hospital. The dependent variable was non-COVID-19 hospital mortality; the independent variables were vaccination status, age, and laboratory data. Serum sodium, age, serum creatinine, and COVID-19 vaccination status were the main independent variables associated with non-COVID-19 mortality. The odds ratio for in-hospital deaths of non-vaccinated patients was 2.01 (1.65–2.44) (unadjusted) and 1.61 (1.29–2.03) after adjustment for the independent variables. This “healthy adherer effect” may confound observational assessments of the clinical efficacy of COVID-19 vaccines.

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