COVID-19 vaccination is associated with reduced non-COVID in-hospital mortality

We retrieved data on a cohort of medical patients at a regional Israeli hospital. The dependent variable was non-COVID-19 hospital mortality; the independent variables were vaccination status, age, and laboratory data. Serum sodium, age, serum creatinine, and COVID-19 vaccination status were the mai...

Descripción completa

Detalles Bibliográficos
Autores principales: Benbassat, Jochanan, Froom, Paul, Shimoni, Zvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625845/
https://www.ncbi.nlm.nih.gov/pubmed/36332771
http://dx.doi.org/10.1016/j.ypmed.2022.107326
_version_ 1784822602676568064
author Benbassat, Jochanan
Froom, Paul
Shimoni, Zvi
author_facet Benbassat, Jochanan
Froom, Paul
Shimoni, Zvi
author_sort Benbassat, Jochanan
collection PubMed
description We retrieved data on a cohort of medical patients at a regional Israeli hospital. The dependent variable was non-COVID-19 hospital mortality; the independent variables were vaccination status, age, and laboratory data. Serum sodium, age, serum creatinine, and COVID-19 vaccination status were the main independent variables associated with non-COVID-19 mortality. The odds ratio for in-hospital deaths of non-vaccinated patients was 2.01 (1.65–2.44) (unadjusted) and 1.61 (1.29–2.03) after adjustment for the independent variables. This “healthy adherer effect” may confound observational assessments of the clinical efficacy of COVID-19 vaccines.
format Online
Article
Text
id pubmed-9625845
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Elsevier Inc.
record_format MEDLINE/PubMed
spelling pubmed-96258452022-11-02 COVID-19 vaccination is associated with reduced non-COVID in-hospital mortality Benbassat, Jochanan Froom, Paul Shimoni, Zvi Prev Med Short Communication We retrieved data on a cohort of medical patients at a regional Israeli hospital. The dependent variable was non-COVID-19 hospital mortality; the independent variables were vaccination status, age, and laboratory data. Serum sodium, age, serum creatinine, and COVID-19 vaccination status were the main independent variables associated with non-COVID-19 mortality. The odds ratio for in-hospital deaths of non-vaccinated patients was 2.01 (1.65–2.44) (unadjusted) and 1.61 (1.29–2.03) after adjustment for the independent variables. This “healthy adherer effect” may confound observational assessments of the clinical efficacy of COVID-19 vaccines. Elsevier Inc. 2022-11 2022-11-02 /pmc/articles/PMC9625845/ /pubmed/36332771 http://dx.doi.org/10.1016/j.ypmed.2022.107326 Text en © 2022 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Short Communication
Benbassat, Jochanan
Froom, Paul
Shimoni, Zvi
COVID-19 vaccination is associated with reduced non-COVID in-hospital mortality
title COVID-19 vaccination is associated with reduced non-COVID in-hospital mortality
title_full COVID-19 vaccination is associated with reduced non-COVID in-hospital mortality
title_fullStr COVID-19 vaccination is associated with reduced non-COVID in-hospital mortality
title_full_unstemmed COVID-19 vaccination is associated with reduced non-COVID in-hospital mortality
title_short COVID-19 vaccination is associated with reduced non-COVID in-hospital mortality
title_sort covid-19 vaccination is associated with reduced non-covid in-hospital mortality
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625845/
https://www.ncbi.nlm.nih.gov/pubmed/36332771
http://dx.doi.org/10.1016/j.ypmed.2022.107326
work_keys_str_mv AT benbassatjochanan covid19vaccinationisassociatedwithreducednoncovidinhospitalmortality
AT froompaul covid19vaccinationisassociatedwithreducednoncovidinhospitalmortality
AT shimonizvi covid19vaccinationisassociatedwithreducednoncovidinhospitalmortality

Ejemplares similares