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Open Retroperitoneal Repair for Complex Abdominal Aortic Aneurysms

Background  Open surgical repair (OSR) of complex abdominal aortic aneurysms (CAAAs) can be challenging. We frequently utilize the retroperitoneal (RP) approach for such cases. We audited our outcomes with the aim of establishing the utility and safety of this approach. Methods  Retrospective analys...

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Autores principales: Hossack, Martin, Simpson, Gregory, Shaw, Penelope, Fisher, Robert, Torella, Francesco, Brennan, John, Smout, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical Publishers, Inc. 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626034/
https://www.ncbi.nlm.nih.gov/pubmed/36318932
http://dx.doi.org/10.1055/s-0042-1748959
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author Hossack, Martin
Simpson, Gregory
Shaw, Penelope
Fisher, Robert
Torella, Francesco
Brennan, John
Smout, Jonathan
author_facet Hossack, Martin
Simpson, Gregory
Shaw, Penelope
Fisher, Robert
Torella, Francesco
Brennan, John
Smout, Jonathan
author_sort Hossack, Martin
collection PubMed
description Background  Open surgical repair (OSR) of complex abdominal aortic aneurysms (CAAAs) can be challenging. We frequently utilize the retroperitoneal (RP) approach for such cases. We audited our outcomes with the aim of establishing the utility and safety of this approach. Methods  Retrospective analysis was performed of all patients undergoing OSR of an unruptured CAAA via a RP approach in our center over a 7-year period. Data on repairs via a transperitoneal (TP) approach were collected to provide context. Demographic, operative, radiological, and biochemical data were collected. The primary outcome measure was 30-day/inpatient mortality. Secondary outcomes included the need for reoperation, incidence of postoperative chest infection, acute kidney injury (AKI) and length of stay (LOS). All patients received aortic clamping above at least one main renal artery. Results  One hundred and three patients underwent OSR of an unruptured CAAA; 55 via a RP approach, 48 TP. The RP group demonstrated a more advanced pattern of disease with a larger median maximum diameter (65 vs. 61 mm, p = 0.013) and a more proximal extent. Consequently, the rate of supravisceral clamping was higher in RP repair (66 vs. 15%, p  < 0.001). Despite this there were no differences in the observed early mortality (9.1 vs. 10%, NS); incidence of reoperation (10.9 vs. 12.5%, NS), chest infection (32.7 vs. 25%, NS), and AKI (52.7 vs. 45.8%, NS); or median LOS (10 vs. 12 days, NS) following RP and TP repair. Conclusion  OSR of CAAAs carries significant 30-day mortality. In patients unsuitable for fenestrated endovascular aortic repair or those desiring a durable long-term solution, OSR can be performed through the RP or TP approach. This study has demonstrated that in our unit RP repair facilitates treatment of more advanced AAA utilizing complex proximal clamp zones with similar perioperative morbidity and mortality compared with TP cases utilizing more distal clamping.
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spelling pubmed-96260342022-11-02 Open Retroperitoneal Repair for Complex Abdominal Aortic Aneurysms Hossack, Martin Simpson, Gregory Shaw, Penelope Fisher, Robert Torella, Francesco Brennan, John Smout, Jonathan Aorta (Stamford) Background  Open surgical repair (OSR) of complex abdominal aortic aneurysms (CAAAs) can be challenging. We frequently utilize the retroperitoneal (RP) approach for such cases. We audited our outcomes with the aim of establishing the utility and safety of this approach. Methods  Retrospective analysis was performed of all patients undergoing OSR of an unruptured CAAA via a RP approach in our center over a 7-year period. Data on repairs via a transperitoneal (TP) approach were collected to provide context. Demographic, operative, radiological, and biochemical data were collected. The primary outcome measure was 30-day/inpatient mortality. Secondary outcomes included the need for reoperation, incidence of postoperative chest infection, acute kidney injury (AKI) and length of stay (LOS). All patients received aortic clamping above at least one main renal artery. Results  One hundred and three patients underwent OSR of an unruptured CAAA; 55 via a RP approach, 48 TP. The RP group demonstrated a more advanced pattern of disease with a larger median maximum diameter (65 vs. 61 mm, p = 0.013) and a more proximal extent. Consequently, the rate of supravisceral clamping was higher in RP repair (66 vs. 15%, p  < 0.001). Despite this there were no differences in the observed early mortality (9.1 vs. 10%, NS); incidence of reoperation (10.9 vs. 12.5%, NS), chest infection (32.7 vs. 25%, NS), and AKI (52.7 vs. 45.8%, NS); or median LOS (10 vs. 12 days, NS) following RP and TP repair. Conclusion  OSR of CAAAs carries significant 30-day mortality. In patients unsuitable for fenestrated endovascular aortic repair or those desiring a durable long-term solution, OSR can be performed through the RP or TP approach. This study has demonstrated that in our unit RP repair facilitates treatment of more advanced AAA utilizing complex proximal clamp zones with similar perioperative morbidity and mortality compared with TP cases utilizing more distal clamping. Thieme Medical Publishers, Inc. 2022-11-01 /pmc/articles/PMC9626034/ /pubmed/36318932 http://dx.doi.org/10.1055/s-0042-1748959 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ ) https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Hossack, Martin
Simpson, Gregory
Shaw, Penelope
Fisher, Robert
Torella, Francesco
Brennan, John
Smout, Jonathan
Open Retroperitoneal Repair for Complex Abdominal Aortic Aneurysms
title Open Retroperitoneal Repair for Complex Abdominal Aortic Aneurysms
title_full Open Retroperitoneal Repair for Complex Abdominal Aortic Aneurysms
title_fullStr Open Retroperitoneal Repair for Complex Abdominal Aortic Aneurysms
title_full_unstemmed Open Retroperitoneal Repair for Complex Abdominal Aortic Aneurysms
title_short Open Retroperitoneal Repair for Complex Abdominal Aortic Aneurysms
title_sort open retroperitoneal repair for complex abdominal aortic aneurysms
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626034/
https://www.ncbi.nlm.nih.gov/pubmed/36318932
http://dx.doi.org/10.1055/s-0042-1748959
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