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Open Retroperitoneal Repair for Complex Abdominal Aortic Aneurysms
Background Open surgical repair (OSR) of complex abdominal aortic aneurysms (CAAAs) can be challenging. We frequently utilize the retroperitoneal (RP) approach for such cases. We audited our outcomes with the aim of establishing the utility and safety of this approach. Methods Retrospective analys...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Thieme Medical Publishers, Inc.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626034/ https://www.ncbi.nlm.nih.gov/pubmed/36318932 http://dx.doi.org/10.1055/s-0042-1748959 |
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author | Hossack, Martin Simpson, Gregory Shaw, Penelope Fisher, Robert Torella, Francesco Brennan, John Smout, Jonathan |
author_facet | Hossack, Martin Simpson, Gregory Shaw, Penelope Fisher, Robert Torella, Francesco Brennan, John Smout, Jonathan |
author_sort | Hossack, Martin |
collection | PubMed |
description | Background Open surgical repair (OSR) of complex abdominal aortic aneurysms (CAAAs) can be challenging. We frequently utilize the retroperitoneal (RP) approach for such cases. We audited our outcomes with the aim of establishing the utility and safety of this approach. Methods Retrospective analysis was performed of all patients undergoing OSR of an unruptured CAAA via a RP approach in our center over a 7-year period. Data on repairs via a transperitoneal (TP) approach were collected to provide context. Demographic, operative, radiological, and biochemical data were collected. The primary outcome measure was 30-day/inpatient mortality. Secondary outcomes included the need for reoperation, incidence of postoperative chest infection, acute kidney injury (AKI) and length of stay (LOS). All patients received aortic clamping above at least one main renal artery. Results One hundred and three patients underwent OSR of an unruptured CAAA; 55 via a RP approach, 48 TP. The RP group demonstrated a more advanced pattern of disease with a larger median maximum diameter (65 vs. 61 mm, p = 0.013) and a more proximal extent. Consequently, the rate of supravisceral clamping was higher in RP repair (66 vs. 15%, p < 0.001). Despite this there were no differences in the observed early mortality (9.1 vs. 10%, NS); incidence of reoperation (10.9 vs. 12.5%, NS), chest infection (32.7 vs. 25%, NS), and AKI (52.7 vs. 45.8%, NS); or median LOS (10 vs. 12 days, NS) following RP and TP repair. Conclusion OSR of CAAAs carries significant 30-day mortality. In patients unsuitable for fenestrated endovascular aortic repair or those desiring a durable long-term solution, OSR can be performed through the RP or TP approach. This study has demonstrated that in our unit RP repair facilitates treatment of more advanced AAA utilizing complex proximal clamp zones with similar perioperative morbidity and mortality compared with TP cases utilizing more distal clamping. |
format | Online Article Text |
id | pubmed-9626034 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Thieme Medical Publishers, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-96260342022-11-02 Open Retroperitoneal Repair for Complex Abdominal Aortic Aneurysms Hossack, Martin Simpson, Gregory Shaw, Penelope Fisher, Robert Torella, Francesco Brennan, John Smout, Jonathan Aorta (Stamford) Background Open surgical repair (OSR) of complex abdominal aortic aneurysms (CAAAs) can be challenging. We frequently utilize the retroperitoneal (RP) approach for such cases. We audited our outcomes with the aim of establishing the utility and safety of this approach. Methods Retrospective analysis was performed of all patients undergoing OSR of an unruptured CAAA via a RP approach in our center over a 7-year period. Data on repairs via a transperitoneal (TP) approach were collected to provide context. Demographic, operative, radiological, and biochemical data were collected. The primary outcome measure was 30-day/inpatient mortality. Secondary outcomes included the need for reoperation, incidence of postoperative chest infection, acute kidney injury (AKI) and length of stay (LOS). All patients received aortic clamping above at least one main renal artery. Results One hundred and three patients underwent OSR of an unruptured CAAA; 55 via a RP approach, 48 TP. The RP group demonstrated a more advanced pattern of disease with a larger median maximum diameter (65 vs. 61 mm, p = 0.013) and a more proximal extent. Consequently, the rate of supravisceral clamping was higher in RP repair (66 vs. 15%, p < 0.001). Despite this there were no differences in the observed early mortality (9.1 vs. 10%, NS); incidence of reoperation (10.9 vs. 12.5%, NS), chest infection (32.7 vs. 25%, NS), and AKI (52.7 vs. 45.8%, NS); or median LOS (10 vs. 12 days, NS) following RP and TP repair. Conclusion OSR of CAAAs carries significant 30-day mortality. In patients unsuitable for fenestrated endovascular aortic repair or those desiring a durable long-term solution, OSR can be performed through the RP or TP approach. This study has demonstrated that in our unit RP repair facilitates treatment of more advanced AAA utilizing complex proximal clamp zones with similar perioperative morbidity and mortality compared with TP cases utilizing more distal clamping. Thieme Medical Publishers, Inc. 2022-11-01 /pmc/articles/PMC9626034/ /pubmed/36318932 http://dx.doi.org/10.1055/s-0042-1748959 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ ) https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Hossack, Martin Simpson, Gregory Shaw, Penelope Fisher, Robert Torella, Francesco Brennan, John Smout, Jonathan Open Retroperitoneal Repair for Complex Abdominal Aortic Aneurysms |
title | Open Retroperitoneal Repair for Complex Abdominal Aortic Aneurysms |
title_full | Open Retroperitoneal Repair for Complex Abdominal Aortic Aneurysms |
title_fullStr | Open Retroperitoneal Repair for Complex Abdominal Aortic Aneurysms |
title_full_unstemmed | Open Retroperitoneal Repair for Complex Abdominal Aortic Aneurysms |
title_short | Open Retroperitoneal Repair for Complex Abdominal Aortic Aneurysms |
title_sort | open retroperitoneal repair for complex abdominal aortic aneurysms |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626034/ https://www.ncbi.nlm.nih.gov/pubmed/36318932 http://dx.doi.org/10.1055/s-0042-1748959 |
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