Holmium-166 Radioembolization: Current Status and Future Prospective

Since its first suggestion as possible option for liver radioembolization treatment, the therapeutic isotope holmium-166 ((166)Ho) caught the experts’ attention due to its imaging possibilities. Being not only a beta, but also a gamma emitter and a lanthanide, (166)Ho can be imaged using single-phot...

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Autores principales: Stella, Martina, Braat, Arthur J. A. T., van Rooij, Rob, de Jong, Hugo W. A. M., Lam, Marnix G. E. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626412/
https://www.ncbi.nlm.nih.gov/pubmed/35729423
http://dx.doi.org/10.1007/s00270-022-03187-y
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author Stella, Martina
Braat, Arthur J. A. T.
van Rooij, Rob
de Jong, Hugo W. A. M.
Lam, Marnix G. E. H.
author_facet Stella, Martina
Braat, Arthur J. A. T.
van Rooij, Rob
de Jong, Hugo W. A. M.
Lam, Marnix G. E. H.
author_sort Stella, Martina
collection PubMed
description Since its first suggestion as possible option for liver radioembolization treatment, the therapeutic isotope holmium-166 ((166)Ho) caught the experts’ attention due to its imaging possibilities. Being not only a beta, but also a gamma emitter and a lanthanide, (166)Ho can be imaged using single-photon emission computed tomography and magnetic resonance imaging, respectively. Another advantage of (166)Ho is the possibility to perform the scout and treatment procedure with the same particle. This prospect paves the way to an individualized treatment procedure, gaining more control over dosimetry-based patient selection and treatment planning. In this review, an overview on (166)Ho liver radioembolization will be presented. The current clinical workflow, together with the most relevant clinical findings and the future prospective will be provided.
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spelling pubmed-96264122022-11-03 Holmium-166 Radioembolization: Current Status and Future Prospective Stella, Martina Braat, Arthur J. A. T. van Rooij, Rob de Jong, Hugo W. A. M. Lam, Marnix G. E. H. Cardiovasc Intervent Radiol Review Since its first suggestion as possible option for liver radioembolization treatment, the therapeutic isotope holmium-166 ((166)Ho) caught the experts’ attention due to its imaging possibilities. Being not only a beta, but also a gamma emitter and a lanthanide, (166)Ho can be imaged using single-photon emission computed tomography and magnetic resonance imaging, respectively. Another advantage of (166)Ho is the possibility to perform the scout and treatment procedure with the same particle. This prospect paves the way to an individualized treatment procedure, gaining more control over dosimetry-based patient selection and treatment planning. In this review, an overview on (166)Ho liver radioembolization will be presented. The current clinical workflow, together with the most relevant clinical findings and the future prospective will be provided. Springer US 2022-06-21 2022 /pmc/articles/PMC9626412/ /pubmed/35729423 http://dx.doi.org/10.1007/s00270-022-03187-y Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Stella, Martina
Braat, Arthur J. A. T.
van Rooij, Rob
de Jong, Hugo W. A. M.
Lam, Marnix G. E. H.
Holmium-166 Radioembolization: Current Status and Future Prospective
title Holmium-166 Radioembolization: Current Status and Future Prospective
title_full Holmium-166 Radioembolization: Current Status and Future Prospective
title_fullStr Holmium-166 Radioembolization: Current Status and Future Prospective
title_full_unstemmed Holmium-166 Radioembolization: Current Status and Future Prospective
title_short Holmium-166 Radioembolization: Current Status and Future Prospective
title_sort holmium-166 radioembolization: current status and future prospective
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626412/
https://www.ncbi.nlm.nih.gov/pubmed/35729423
http://dx.doi.org/10.1007/s00270-022-03187-y
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