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A functional eEF2K-eEF2 pathway in the NAc is critical for the expression of cocaine-induced psychomotor sensitisation and conditioned place preference

Recent evidence links synaptic plasticity and mRNA translation, via the eukaryotic elongation factor 2 kinase (eEF2K) and its only known substrate, eEF2. However, the involvement of the eEF2 pathway in cocaine-induced neuroadaptations and cocaine-induced behaviours is not known. Knock-in (KI) mice a...

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Detalles Bibliográficos
Autores principales:	Beiser, Tehila, Lisniansky, Elvira, Weitz, Moriya, Bingor, Alexey, Grad, Etty, Rosenblum, Kobi, Thornton, Claire, Yaka, Rami
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626485/ https://www.ncbi.nlm.nih.gov/pubmed/36319619 http://dx.doi.org/10.1038/s41398-022-02232-1

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