FOXQ1 recruits the MLL complex to activate transcription of EMT and promote breast cancer metastasis

Aberrant expression of the Forkhead box transcription factor, FOXQ1, is a prevalent mechanism of epithelial-mesenchymal transition (EMT) and metastasis in multiple carcinoma types. However, it remains unknown how FOXQ1 regulates gene expression. Here, we report that FOXQ1 initiates EMT by recruiting...

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Detalles Bibliográficos
Autores principales: Mitchell, Allison V., Wu, Ling, James Block, C., Zhang, Mu, Hackett, Justin, Craig, Douglas B., Chen, Wei, Zhao, Yongzhong, Zhang, Bin, Dang, Yongjun, Zhang, Xiaohong, Zhang, Shengping, Wang, Chuangui, Gibson, Heather, Pile, Lori A., Kidder, Benjamin, Matherly, Larry, Yang, Zhe, Dou, Yali, Wu, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626503/
https://www.ncbi.nlm.nih.gov/pubmed/36319643
http://dx.doi.org/10.1038/s41467-022-34239-z

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