Cargando…

Combining bulk RNA-sequencing and single-cell RNA-sequencing data to reveal the immune microenvironment and metabolic pattern of osteosarcoma

Background: Osteosarcoma (OS) is a kind of solid tumor with high heterogeneity at tumor microenvironment (TME), genome and transcriptome level. In view of the regulatory effect of metabolism on TME, this study was based on four metabolic models to explore the intertumoral heterogeneity of OS at the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Ruichao, Wang, Xiaohu, Yin, Xiangyun, Zhou, Yaqi, Sun, Jiansheng, Yin, Zhongxiu, Zhu, Zhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626532/ https://www.ncbi.nlm.nih.gov/pubmed/36338972 http://dx.doi.org/10.3389/fgene.2022.976990

Ejemplares similares

Integrated analysis of single-cell and bulk RNA sequencing data reveals an immunostimulatory microenvironment in tumor thrombus of osteosarcoma
por: Ji, Tao, et al.
Publicado: (2023)

Integration of Single-Cell RNA Sequencing and Bulk RNA Sequencing Data to Establish and Validate a Prognostic Model for Patients With Lung Adenocarcinoma
por: Jiang, Aimin, et al.
Publicado: (2022)

Single-Cell RNA-Seq and Bulk RNA-Seq Reveal Intratumoral Heterogeneity and Tumor Microenvironment Characteristics in Diffuse Large B-Cell Lymphoma
por: Zhao, Yang, et al.
Publicado: (2022)

RNA-sequencing analysis reveals the long noncoding RNA profile in the mouse myopic retina
por: Li, Yuanjun, et al.
Publicado: (2022)

Combined analysis of single-cell and bulk RNA sequencing reveals the expression patterns of circadian rhythm disruption in the immune microenvironment of Alzheimer’s disease
por: He, Huiling, et al.
Publicado: (2023)

Reference Transcriptomes of Porcine Peripheral Immune Cells Created Through Bulk and Single-Cell RNA Sequencing
por: Herrera-Uribe, Juber, et al.
Publicado: (2021)

Single-cell and bulk RNA sequencing reveals Anoikis related genes to guide prognosis and immunotherapy in osteosarcoma
por: Zhong, Cheng, et al.
Publicado: (2023)

Neuroendocrinology of the lung revealed by single-cell RNA sequencing
por: Kuo, Christin S, et al.
Publicado: (2022)

Integrated analysis of bulk and single-cell RNA sequencing reveals the interaction of PKP1 and tumor-infiltrating B cells and their therapeutic potential for nasopharyngeal carcinoma
por: Huang, Yu-Mei, et al.
Publicado: (2022)

Integrated single-cell and bulk RNA sequencing analyses reveal a prognostic signature of cancer-associated fibroblasts in head and neck squamous cell carcinoma
por: Yang, Yichen, et al.
Publicado: (2022)

Prognosis Prediction Through an Integrated Analysis of Single-Cell and Bulk RNA-Sequencing Data in Triple-Negative Breast Cancer
por: Wang, Xiangru, et al.
Publicado: (2022)

Integration of single-cell RNA sequencing and bulk RNA sequencing to reveal an immunogenic cell death-related 5-gene panel as a prognostic model for osteosarcoma
por: Yang, Jiaqi, et al.
Publicado: (2022)

Comprehensive analysis of potential cellular communication networks in advanced osteosarcoma using single-cell RNA sequencing data
por: Xu, Ning, et al.
Publicado: (2022)

Combining bulk and single-cell RNA-sequencing data to reveal gene expression pattern of chondrocytes in the osteoarthritic knee
por: Li, Xiaoyu, et al.
Publicado: (2021)

Identification of a Recurrence Gene Signature for Ovarian Cancer Prognosis by Integrating Single-Cell RNA Sequencing and Bulk Expression Datasets
por: Zhang, Yongjian, et al.
Publicado: (2022)

Identification of differentially expressed genes at the single-cell level and prognosis prediction through bulk RNA sequencing data in breast cancer
por: Chen, Hanghang, et al.
Publicado: (2022)

Construction of a circRNA-miRNA-mRNA Regulatory Network Reveals Potential Mechanism and Treatment Options for Osteosarcoma
por: He, Yi, et al.
Publicado: (2021)

Identification of a Novel Deep Intronic Variant by Whole Genome Sequencing Combined With RNA Sequencing in a Chinese Patient With Menkes Disease
por: Zhi, Xiufang, et al.
Publicado: (2022)

Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With Traumatic Brain Injury
por: Xing, Jin, et al.
Publicado: (2022)

Evaluation of CircRNA Sequence Assembly Methods Using Long Reads
por: Zhang, Jingjing, et al.
Publicado: (2022)

Identification of novel tumor microenvironment-associated genes in gastric cancer based on single-cell RNA-sequencing datasets
por: Wei, Xujin, et al.
Publicado: (2022)

Comprehensive analysis of mitophagy-related genes in diagnosis and heterogeneous endothelial cells in chronic rhinosinusitis: based on bulk and single-cell RNA sequencing data
por: Zhou, Shican, et al.
Publicado: (2023)

Integrated analysis of bulk and single-cell RNA-seq reveals the role of MYC signaling in lung adenocarcinoma
por: Hao, Lu, et al.
Publicado: (2022)

Single-cell RNA Sequencing Reveals Heterogeneity of Cultured Bovine Satellite Cells
por: Lyu, Pengcheng, et al.
Publicado: (2021)

Small RNA sequencing reveals sex-related miRNAs in Collichthys lucidus
por: Song, Wei, et al.
Publicado: (2022)

Integrated mRNA and Small RNA Sequencing Reveals microRNAs Associated With Xylem Development in Dalbergia odorifera
por: Zhao, Wenxiu, et al.
Publicado: (2022)

Editorial: Multimodal and Integrative Analysis of Single-Cell or Bulk Sequencing Data
por: Chen, Geng
Publicado: (2021)

Sequence variant analysis of RNA sequences in severe equine asthma
por: Tessier, Laurence, et al.
Publicado: (2018)

Corrigendum: Evaluation of CircRNA sequence assembly methods using long reads
por: Zhang, Jingjing, et al.
Publicado: (2023)

8-Gene signature related to CD8(+) T cell infiltration by integrating single-cell and bulk RNA-sequencing in head and neck squamous cell carcinoma
por: Zhang, Shoujing, et al.
Publicado: (2022)

A novel endothelial-related prognostic index by integrating single-cell and bulk RNA sequencing data for patients with kidney renal clear cell carcinoma
por: Li, Deng-Xiong, et al.
Publicado: (2023)

Integrating Bulk Transcriptome and Single-Cell RNA Sequencing Data Reveals the Landscape of the Immune Microenvironment in Thoracic Aortic Aneurysms
por: Wang, Qunhui, et al.
Publicado: (2022)

Analysis of characteristic genes and ceRNA regulation mechanism of endometriosis based on full transcriptional sequencing
por: Xie, Chengmao, et al.
Publicado: (2022)

RNA modification writers pattern in relation to tumor microenvironment and prognosis in prostate cancer
por: Cheng, Xu, et al.
Publicado: (2023)

Editorial: Integrative analysis of single-cell and/or bulk multi-omics sequencing data
por: Chen, Geng, et al.
Publicado: (2023)

A Novel Pyroptosis-Related Signature for Predicting Prognosis and Indicating Immune Microenvironment Features in Osteosarcoma
por: Zhang, Yiming, et al.
Publicado: (2021)

CXCR4 Expressed by Tumor-Infiltrating B Cells in Gastric Cancer Related to Survival in the Tumor Microenvironment: An Analysis Combining Single-Cell RNA Sequencing with Bulk RNA Sequencing
por: Su, Chen, et al.
Publicado: (2023)

NISC: Neural Network-Imputation for Single-Cell RNA Sequencing and Cell Type Clustering
por: Zhang, Xiang, et al.
Publicado: (2022)

Combined transient ablation and single-cell RNA-sequencing reveals the development of medullary thymic epithelial cells
por: Wells, Kristen L, et al.
Publicado: (2020)

Single-cell RNA-sequencing combined with bulk RNA-sequencing analysis of peripheral blood reveals the characteristics and key immune cell genes of ulcerative colitis
por: Dai, Yan-Cheng, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_dkohi8581msd50rkdeukc1r2l6