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Testis-expressed gene 11 inhibits cisplatin-induced DNA damage and contributes to chemoresistance in testicular germ cell tumor

Testicular germ cell tumor (TGCT) is a rare cancer but the most common tumor among adolescent and young adult males. Patients with advanced TGCT often exhibit a worse prognosis due to the acquisition of therapeutic resistance. Cisplatin-based chemotherapy is a standard treatment for advanced TGCTs i...

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Detalles Bibliográficos
Autores principales: Kitayama, Sachi, Ikeda, Kazuhiro, Sato, Wataru, Takeshita, Hideki, Kawakami, Satoru, Inoue, Satoshi, Horie, Kuniko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626550/
https://www.ncbi.nlm.nih.gov/pubmed/36319719
http://dx.doi.org/10.1038/s41598-022-21856-3

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