HIV-1 Rev-RRE functional activity in primary isolates is highly dependent on minimal context-dependent changes in Rev

During HIV infection, intron-containing viral mRNAs are exported from the cell nucleus to the cytoplasm to complete the replication cycle. Cellular restrictions on the export of incompletely spliced transcripts are overcome by a viral protein, Rev, and an RNA structure found in all unspliced and inc...

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Detalles Bibliográficos
Autores principales: Dzhivhuho, Godfrey, Holsey, Jordan, Honeycutt, Ethan, O’Farrell, Heather, Rekosh, David, Hammarskjold, Marie-Louise, Jackson, Patrick E. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626594/
https://www.ncbi.nlm.nih.gov/pubmed/36319640
http://dx.doi.org/10.1038/s41598-022-21714-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626594/
https://www.ncbi.nlm.nih.gov/pubmed/36319640
http://dx.doi.org/10.1038/s41598-022-21714-2

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