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An electrocardiography score predicts heart failure hospitalization or death beyond that of cardiovascular magnetic resonance imaging
The electrocardiogram (ECG) and cardiovascular magnetic resonance imaging (CMR) provide powerful prognostic information. The aim was to determine their relative prognostic value. Patients (n = 783) undergoing CMR and 12-lead ECG with a QRS duration < 120 ms were included. Prognosis scores for one...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626618/ https://www.ncbi.nlm.nih.gov/pubmed/36319723 http://dx.doi.org/10.1038/s41598-022-22501-9 |
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author | Maanja, Maren Schlegel, Todd T. Fröjdh, Fredrika Niklasson, Louise Wieslander, Björn Bacharova, Ljuba Schelbert, Erik B. Ugander, Martin |
author_facet | Maanja, Maren Schlegel, Todd T. Fröjdh, Fredrika Niklasson, Louise Wieslander, Björn Bacharova, Ljuba Schelbert, Erik B. Ugander, Martin |
author_sort | Maanja, Maren |
collection | PubMed |
description | The electrocardiogram (ECG) and cardiovascular magnetic resonance imaging (CMR) provide powerful prognostic information. The aim was to determine their relative prognostic value. Patients (n = 783) undergoing CMR and 12-lead ECG with a QRS duration < 120 ms were included. Prognosis scores for one-year event-free survival from hospitalization for heart failure or death were derived using continuous ECG or CMR measures, and multivariable logistic regression, and compared. Patients (median [interquartile range] age 55 [43–64] years, 44% female) had 155 events during 5.7 [4.4–6.6] years. The ECG prognosis score included (1) frontal plane QRS-T angle, and (2) heart rate corrected QT duration (QTc) (log-rank 55). The CMR prognosis score included (1) global longitudinal strain, and (2) extracellular volume fraction (log-rank 85). The combination of positive scores for both ECG and CMR yielded the highest prognostic value (log-rank 105). Multivariable analysis showed an association with outcomes for both the ECG prognosis score (log-rank 8.4, hazard ratio [95% confidence interval] 1.29 [1.09–1.54]) and the CMR prognosis score (log-rank 47, hazard ratio 1.90 [1.58–2.28]). An ECG prognosis score predicted outcomes independently of CMR. Combining the results of ECG and CMR using both prognosis scores improved the overall prognostic performance. |
format | Online Article Text |
id | pubmed-9626618 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-96266182022-11-03 An electrocardiography score predicts heart failure hospitalization or death beyond that of cardiovascular magnetic resonance imaging Maanja, Maren Schlegel, Todd T. Fröjdh, Fredrika Niklasson, Louise Wieslander, Björn Bacharova, Ljuba Schelbert, Erik B. Ugander, Martin Sci Rep Article The electrocardiogram (ECG) and cardiovascular magnetic resonance imaging (CMR) provide powerful prognostic information. The aim was to determine their relative prognostic value. Patients (n = 783) undergoing CMR and 12-lead ECG with a QRS duration < 120 ms were included. Prognosis scores for one-year event-free survival from hospitalization for heart failure or death were derived using continuous ECG or CMR measures, and multivariable logistic regression, and compared. Patients (median [interquartile range] age 55 [43–64] years, 44% female) had 155 events during 5.7 [4.4–6.6] years. The ECG prognosis score included (1) frontal plane QRS-T angle, and (2) heart rate corrected QT duration (QTc) (log-rank 55). The CMR prognosis score included (1) global longitudinal strain, and (2) extracellular volume fraction (log-rank 85). The combination of positive scores for both ECG and CMR yielded the highest prognostic value (log-rank 105). Multivariable analysis showed an association with outcomes for both the ECG prognosis score (log-rank 8.4, hazard ratio [95% confidence interval] 1.29 [1.09–1.54]) and the CMR prognosis score (log-rank 47, hazard ratio 1.90 [1.58–2.28]). An ECG prognosis score predicted outcomes independently of CMR. Combining the results of ECG and CMR using both prognosis scores improved the overall prognostic performance. Nature Publishing Group UK 2022-11-01 /pmc/articles/PMC9626618/ /pubmed/36319723 http://dx.doi.org/10.1038/s41598-022-22501-9 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Maanja, Maren Schlegel, Todd T. Fröjdh, Fredrika Niklasson, Louise Wieslander, Björn Bacharova, Ljuba Schelbert, Erik B. Ugander, Martin An electrocardiography score predicts heart failure hospitalization or death beyond that of cardiovascular magnetic resonance imaging |
title | An electrocardiography score predicts heart failure hospitalization or death beyond that of cardiovascular magnetic resonance imaging |
title_full | An electrocardiography score predicts heart failure hospitalization or death beyond that of cardiovascular magnetic resonance imaging |
title_fullStr | An electrocardiography score predicts heart failure hospitalization or death beyond that of cardiovascular magnetic resonance imaging |
title_full_unstemmed | An electrocardiography score predicts heart failure hospitalization or death beyond that of cardiovascular magnetic resonance imaging |
title_short | An electrocardiography score predicts heart failure hospitalization or death beyond that of cardiovascular magnetic resonance imaging |
title_sort | electrocardiography score predicts heart failure hospitalization or death beyond that of cardiovascular magnetic resonance imaging |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626618/ https://www.ncbi.nlm.nih.gov/pubmed/36319723 http://dx.doi.org/10.1038/s41598-022-22501-9 |
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