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Targeting PTEN but not SOCS3 resists an age-dependent decline in promoting axon sprouting
Axonal repair is critical for functional recovery after injury of the CNS. We previously reported that neuronal PTEN deletion exhibits an age-dependent decline in promoting axon regeneration from the corticospinal tract (CST). How sprouting of uninjured axons, a naturally occurring form of axonal re...
Autores principales: | Geoffroy, Cédric G., Meves, Jessica M., Kim, Hugo Jae Mun, Romaus-Sanjurjo, Daniel, Sutherland, Theresa C., Li, Jeffrey J., Suen, Juliet, Sanchez, Joshua J., Zheng, Binhai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626739/ https://www.ncbi.nlm.nih.gov/pubmed/36339257 http://dx.doi.org/10.1016/j.isci.2022.105383 |
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